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Glutamate receptor ionotropic, kainate 1

Summary

UniProt ID

P22756

Gene Symbol

Glur5
Grik1

Gene ID

29559

Organism

Rattus norvegicus (Norway rat)

External Links

PubChem: P22756
Re-Glyco: P22756

Annotation

Keyword

3D-structure
Alternative splicing
Cell membrane
Disulfide bond
Glycoprotein
Ligand-gated ion channel
Phosphoprotein
Postsynaptic cell membrane
RNA editing
Receptor
Reference proteome
Signal
Transmembrane helix

Gene Ontology (GO)

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GO Term
glutamatergic synapse
ionotropic glutamate receptor complex
postsynaptic density
presynaptic membrane
terminal bouton
postsynaptic density membrane
kainate selective glutamate receptor complex
plasma membrane
membrane
dendrite

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

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GO Term
negative regulation of synaptic transmission, glutamatergic
excitatory postsynaptic potential
presynaptic modulation of chemical synaptic transmission
chemical synaptic transmission
nervous system development
gamma-aminobutyric acid secretion
positive regulation of gamma-aminobutyric acid secretion
negative regulation of synaptic transmission, GABAergic
positive regulation of synaptic transmission, GABAergic
synaptic transmission, glutamatergic

Displaying entries **1 - 10** of 11 in total

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GO Term
extracellularly glutamate-gated ion channel activity
SNARE binding
kainate selective glutamate receptor activity
glutamate-gated calcium ion channel activity
identical protein binding
scaffold protein binding
transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
glutamate-gated receptor activity
L-glutamate transmembrane transporter activity
glutamate binding

Annotation information from UniProt.

Sequence

MERSTVLIQPGLWTRDTSWTLLYFLCYILPQTSPQVLRIGGIFETVENEPVNVEELAFKFAVTSINRNRTLMPNTTLTYDIQRINLFDSFEASRRACDQLALGVAALFGPSHSSSVSAVQSICNALEVPHIQTRWKHPSVDSRDLFYINLYPDYAAISRAVLDLVLYYNWKTVTVVYEDSTGLIRLQELIKAPSRYNIKIKIRQLPPANKDAKPLLKEMKKSKEFYVIFDCSHETAAEILKQILFMGMMTEYYHYFFTTLDLFALDLELYRYSGVNMTGFRKLNIDNPHVSSIIEKWSMERLQAPPRPETGLLDGMMTTEAALMYDAVYMVAIASHRASQLTVSSLQCHRHKPCALGPRFMNLIKEARWDGLTGRITFNKTDGLRKDFDLDIISLKEEGTEKASGEVSKHLYKVWKKIGIWNSNSGLNMTDGNRDRSNNITDSLANRTLIVTTILEEPYVMYRKSDKPLYGNDRFEAYCLDLLKELSNILGFLYDVKLVPDGKYGAQNDKGEWNGMVKELIDHRADLAVAPLTITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPDIWMYVLLACLGVSCVLFVIARFTPYEWYNPHPCNPDSDVVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGAVRDGSTMTFFKKSKISTYEKMWAFMSSRQQSALVKNSDEGIQRVLTTDYALLMESTSIEYVTQRNCNLTQIGGLIDSKGYGVGTPIGSPYRDKITIAILQLQEEGKLHMMKEKWWRGNGCPEEDSKEASALGVENIGGIFIVLAAGLVLSVFVAIGEFLYKSRKNNDVEQKGKSSRLRFYFRNKVRFHGSKKESLGVEKCLSFNAIMEELGISLKNQKKLKKKSRTKGKSSFTSILTCHQRRTQRKETVA

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 9** entries
Position	Description	Source
68	N-linked (GlcNAc...) asparagine	UniProt
74	N-linked (GlcNAc...) asparagine	UniProt
276	N-linked (GlcNAc...) asparagine	UniProt
379	N-linked (GlcNAc...) asparagine	UniProt
428	N-linked (GlcNAc...) asparagine	UniProt
439	N-linked (GlcNAc...) asparagine	UniProt
446	N-linked (GlcNAc...) asparagine	UniProt
561	N-linked (GlcNAc...) asparagine	UniProt
766	N-linked (GlcNAc...) asparagine	UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 2** entries
Pathway Name	Organism
Activation of Ca-permeable Kainate Receptor	Rattus norvegicus
Activation of Na-permeable kainate receptors	Rattus norvegicus

Disease

Displaying 1 entry
DO ID	Disease Name	Source
DOID:1824	status epilepticus	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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Summary

External Links

Annotation

International Collaboration

Acknowledgements