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MIRAGE
Integrin alpha-6

Summary
UniProt ID
P23229
Gene Symbol
  • ITGA6
Gene ID
3655
Organism
Homo sapiens (human)
GlycoProtDB
GPDB0011624
GlyConnect
GlyGen
P23229
PubChem
P23229
The O-GlcNAc Database
P23229
RaftProt
P23229
O-GlcNAcAtlas
P23229
Re-Glyco
P23229
Annotation
Keyword
  • 3D-structure
  • Alternative splicing
  • Calcium
  • Cell adhesion
  • Cell membrane
  • Cleavage on pair of basic residues
  • Direct protein sequencing
  • Disulfide bond
  • Epidermolysis bullosa
  • Glycoprotein
  • Integrin
  • Metal-binding
  • Palmitate
  • Phosphoprotein
  • Receptor
  • Reference proteome
  • Repeat
  • Signal
  • Transmembrane helix
Gene Ontology (GO)
Displaying all 9 entries
GO Term
plasma membrane
adherens junction
external side of plasma membrane
cell surface
focal adhesion
integrin complex
filopodium
integrin alpha6-beta1 complex
integrin alpha6-beta4 complex
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Annotation information from UniProt.
Sequence
MAAAGQLCLLYLSAGLLSRLGAAFNLDTREDNVIRKYGDPGSLFGFSLAMHWQLQPEDKRLLLVGAPRAEALPLQRANRTGGLYSCDITARGPCTRIEFDNDADPTSESKEDQWMGVTVQSQGPGGKVVTCAHRYEKRQHVNTKQESRDIFGRCYVLSQNLRIEDDMDGGDWSFCDGRLRGHEKFGSCQQGVAATFTKDFHYIVFGAPGTYNWKGIVRVEQKNNTFFDMNIFEDGPYEVGGETEHDESLVPVPANSYLGLLFLTSVSYTDPDQFVYKTRPPREQPDTFPDVMMNSYLGFSLDSGKGIVSKDEITFVSGAPRANHSGAVVLLKRDMKSAHLLPEHIFDGEGLASSFGYDVAVVDLNKDGWQDIVIGAPQYFDRDGEVGGAVYVYMNQQGRWNNVKPIRLNGTKDSMFGIAVKNIGDINQDGYPDIAVGAPYDDLGKVFIYHGSANGINTKPTQVLKGISPYFGYSIAGNMDLDRNSYPDVAVGSLSDSVTIFRSRPVINIQKTITVTPNRIDLRQKTACGAPSGICLQVKSCFEYTANPAGYNPSISIVGTLEAEKERRKSGLSSRVQFRNQGSEPKYTQELTLKRQKQKVCMEETLWLQDNIRDKLRPIPITASVEIQEPSSRRRVNSLPEVLPILNSDEPKTAHIDVHFLKEGCGDDNVCNSNLKLEYKFCTREGNQDKFSYLPIQKGVPELVLKDQKDIALEITVTNSPSNPRNPTKDGDDAHEAKLIATFPDTLTYSAYRELRAFPEKQLSCVANQNGSQADCELGNPFKRNSNVTFYLVLSTTEVTFDTPDLDINLKLETTSNQDNLAPITAKAKVVIELLLSVSGVAKPSQVYFGGTVVGEQAMKSEDEVGSLIEYEFRVINLGKPLTNLGTATLNIQWPKEISNGKWLLYLVKVESKGLEKVTCEPQKEINSLNLTESHNSRKKREITEKQIDDNRKFSLFAERKYQTLNCSVNVNCVNIRCPLRGLDSKASLILRSRLWNSTFLEEYSKLNYLDILMRAFIDVTAAAENIRLPNAGTQVRVTVFPSKTVAQYSGVPWWIILVAILAGILMLALLVFILWKCGFFKRSRYDDSVPRYHAVRIRKEEREIKDEKYIDNLEKKQWITKWNENESYS
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying entries 1 - 10 of 15 in total
Position Description PubMed ID GlyTouCan ID Source
78 N-linked (GlcNAc...) asparagine
223 N-linked (GlcNAc...) asparagine
323 N-linked (GlcNAc...) asparagine
409 N-linked (GlcNAc...) asparagine
452
726
770 N-linked (GlcNAc...) asparagine
787 N-linked (GlcNAc...) asparagine
891
927
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 6 entries
Pathway Name Organism
Assembly of collagen fibrils and other multimeric structures Homo sapiens
Basigin interactions Homo sapiens
Integrin cell surface interactions Homo sapiens
Laminin interactions Homo sapiens
Syndecan interactions Homo sapiens
Type I hemidesmosome assembly Homo sapiens
Disease
Displaying all 2 entries
DO ID Disease Name Source
DOID:0060733 junctional epidermolysis bullosa with pyloric atresia
DOID:3209 junctional epidermolysis bullosa
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025