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Gap junction alpha-1 protein

Summary

UniProt ID

P23242

Gene Symbol

Gja1
Cxn-43

Organism

Mus musculus (house mouse)

External Links

GlyGen: P23242
PubChem: P23242

Annotation

Keyword

Acetylation
Cell membrane
Disulfide bond
Endoplasmic reticulum
Gap junction
Isopeptide bond
Phosphoprotein
Reference proteome
S-nitrosylation
Transmembrane helix
Ubl conjugation

Gene Ontology (GO)

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GO Term
response to glucose
positive regulation of cell communication by chemical coupling
maintenance of protein localization in endoplasmic reticulum
regulation of blood vessel remodeling
cardiac conduction
cellular response to parathyroid hormone stimulus
regulation of actin filament organization
positive regulation of cold-induced thermogenesis
negative regulation of trophoblast cell migration
positive regulation of establishment of Sertoli cell barrier

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GO Term
cytoplasm
mitochondrion
intermediate filament
plasma membrane
cell-cell junction
membrane
cell junction
protein-containing complex
contractile fiber
mitochondrial outer membrane

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GO Term
signaling receptor binding
monoatomic ion transmembrane transporter activity
connexin binding
gap junction channel activity involved in cardiac conduction electrical coupling
gap junction channel activity
SH3 domain binding
protein domain specific binding
gap junction hemi-channel activity
scaffold protein binding
disordered domain specific binding

Annotation information from UniProt.

Sequence

MGDWSALGKLLDKVQAYSTAGGKVWLSVLFIFRILLLGTAVESAWGDEQSAFRCNTQQPGCENVCYDKSFPISHVRFWVLQIIFVSVPTLLYLAHVFYVMRKEEKLNKKEEELKVAQTDGVNVEMHLKQIEIKKFKYGIEEHGKVKMRGGLLRTYIISILFKSVFEVAFLLIQWYIYGFSLSAVYTCKRDPCPHQVDCFLSRPTEKTIFIIFMLVVSLVSLALNIIELFYVFFKGVKDRVKGRSDPYHATTGPLSPSKDCGSPKYAYFNGCSSPTAPLSPMSPPGYKLVTGDRNNSSCRNYNKQASEQNWANYSAEQNRMGQAGSTISNSHAQPFDFPDDSQNAKKVAAGHELQPLAIVDQRPSSRASSRASSRPRPDDLEI

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
312			G02815KT	GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 6** entries
Pathway Name	Organism
Formation of annular gap junctions	Mus musculus
Gap junction assembly	Mus musculus
Gap junction degradation	Mus musculus
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane	Mus musculus
RHOQ GTPase cycle	Mus musculus
Regulation of gap junction activity	Mus musculus