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Gap junction alpha-1 protein
Summary
- UniProt ID
- P23242
- Gene Symbol
-
- Cxn-43
- Gja1
- Gene ID
- 14609
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Acetylation
- Cell membrane
- Disulfide bond
- Endoplasmic reticulum
- Gap junction
- Isopeptide bond
- Phosphoprotein
- Reference proteome
- S-nitrosylation
- Transmembrane helix
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| connexin complex |
| cytoplasm |
| mitochondrion |
| intermediate filament |
| plasma membrane |
| cell-cell junction |
| membrane |
| cell junction |
| contractile fiber |
| nucleoplasm |
| GO Term |
|---|
| beta-catenin binding |
| efflux transmembrane transporter activity |
| tubulin binding |
| PDZ domain binding |
| glutathione transmembrane transporter activity |
| disordered domain specific binding |
Sequence
MGDWSALGKLLDKVQAYSTAGGKVWLSVLFIFRILLLGTAVESAWGDEQSAFRCNTQQPGCENVCYDKSFPISHVRFWVLQIIFVSVPTLLYLAHVFYVMRKEEKLNKKEEELKVAQTDGVNVEMHLKQIEIKKFKYGIEEHGKVKMRGGLLRTYIISILFKSVFEVAFLLIQWYIYGFSLSAVYTCKRDPCPHQVDCFLSRPTEKTIFIIFMLVVSLVSLALNIIELFYVFFKGVKDRVKGRSDPYHATTGPLSPSKDCGSPKYAYFNGCSSPTAPLSPMSPPGYKLVTGDRNNSSCRNYNKQASEQNWANYSAEQNRMGQAGSTISNSHAQPFDFPDDSQNAKKVAAGHELQPLAIVDQRPSSRASSRASSRPRPDDLEI
Glycosylation Sites
G02815KT
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Formation of annular gap junctions | Mus musculus |
| Gap junction assembly | Mus musculus |
| Gap junction degradation | Mus musculus |
| Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane | Mus musculus |
| RHOQ GTPase cycle | Mus musculus |
| Regulation of gap junction activity | Mus musculus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060291 | oculodentodigital dysplasia |
