GlyCosmos Portal

Submissions

Glycine receptor subunit alpha-2

Summary

UniProt ID

P23416

Gene Symbol

GLRA2

Organism

Homo sapiens (human)

External Links

GlyGen: P23416
PubChem: P23416
The Human Metabolome Database: HMDBP08217
O-GlcNAcAtlas: P23416

Annotation

Keyword

3D-structure
Alternative splicing
Cell membrane
Cell projection
Chloride channel
Disease variant
Disulfide bond
Glycoprotein
Intellectual disability
Ligand-gated ion channel
Metal-binding
Postsynaptic cell membrane
Receptor
Reference proteome
Signal
Transmembrane helix
Zinc

Gene Ontology (GO)

Displaying **all 6** entries
GO Term
neuropeptide signaling pathway
monoatomic ion transmembrane transport
cellular response to amino acid stimulus
cellular response to ethanol
chloride transmembrane transport
cellular response to zinc ion

Displaying **all 8** entries
GO Term
plasma membrane
neuron projection
intracellular membrane-bounded organelle
synapse
postsynaptic membrane
glycinergic synapse
transmembrane transporter complex
chloride channel complex

Displaying **all 7** entries
GO Term
transmembrane signaling receptor activity
metal ion binding
glycine binding
neurotransmitter receptor activity
transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
glycine-gated chloride ion channel activity
extracellularly glycine-gated chloride channel activity

Annotation information from UniProt.

Sequence

MNRQLVNILTALFAFFLETNHFRTAFCKDHDSRSGKQPSQTLSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILKEEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQNKEEDVTRESRFNFSGYGMGHCLQVKDGTAVKATPANPLPQPPKDGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITYKIIRHEDVHKK

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites