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MIRAGE
Insulin-like growth factor 1 receptor

Summary
UniProt ID
P24062
Gene Symbol
  • Igf1r
Gene ID
25718
Organism
Rattus norvegicus (Norway rat)
PubChem
P24062
Re-Glyco
P24062
Annotation
Keyword
  • ATP-binding
  • Cell membrane
  • Cleavage on pair of basic residues
  • Disulfide bond
  • Glycoprotein
  • Isopeptide bond
  • Phosphoprotein
  • Receptor
  • Reference proteome
  • Repeat
  • Signal
  • Transmembrane helix
  • Tyrosine-protein kinase
  • Ubl conjugation
Gene Ontology (GO)
Displaying entries 1 - 10 of 13 in total
GO Term
glutamatergic synapse
plasma membrane
membrane
axon
neuronal cell body
intracellular membrane-bounded organelle
receptor complex
postsynapse
T-tubule
insulin receptor complex
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Annotation information from UniProt.
Sequence
MKSGSGGGSPTSLWGLVFLSAALSLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGFLHILLISKAEDYRSYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIFEMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTIDWSLILDAVSNNYIVGNKPPKECGDLCPGTLEEKPMCEKTTINNEYNYRCWTTNRCQKMCPSVCGKRACTENNECCHPECLGSCHTPDDNTTCVACRHYYYKGVCVPACPPGTYRFEGWRCVDRDFCANIPNAESSDSDGFVIHDGECMQECPSGFIRNSTQSMYCIPCEGPCPKVCGDEEKKTKTIDSVTSAQMLQGCTILKGNLLINIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRLILGEEQLEGNYSFYVLDNQNLQQLWDWNHRNLTVRSGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINTRNNGERASCESDVLRFTSTTTWKNRIIITWHRYRPPDYRDLISFTVYYKEAPFKNVTEYDGQDACGSNSWNMVDVDLPPNKEGEPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKSEILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPTLPNGNLSYYIVRWQRQPQDGYLFRHNYCSKDKIPIRKYADGTIDVEEVTENPKTEVCGGDKGPCCACPKTEAEKQAEKEEAEYRKVFENFLHNSIFVPRPERRRRDVLQVANTTMSSRSRNTTVADTYNITDPEEFETEYPFFESRVDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVTWEPRPENSIFLKWPEPENPNGLILMYEIKYGSQVEDQRECVSRQEYRKYGGAKLNRLNPGNYTARIQATSLSGNGSWTDPVFFYVPAKTTYENFMHLIIALPVAILLIVGGLVIMLYVFHRKRNNSRLGNGVLYASVNPEYFSAADVYVPDEWEVAREKITMNRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSLRPEVENNLVLIPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIIGSIKDEMEPSFQEVSFYYSEENKPPEPEELEMELELEPENMESVPLDPSASSASLPLPERHSGHKAENGPGVLVLRASFDERQPYAHMNGGRANERALPLPQSSTC
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying entries 1 - 10 of 16 in total
Position Description PubMed ID GlyTouCan ID Source
51 N-linked (GlcNAc...) asparagine
102 N-linked (GlcNAc...) asparagine
135 N-linked (GlcNAc...) asparagine
245 N-linked (GlcNAc...) asparagine
314 N-linked (GlcNAc...) asparagine
418 N-linked (GlcNAc...) asparagine
439 N-linked (GlcNAc...) asparagine
535 N-linked (GlcNAc...) asparagine
608 N-linked (GlcNAc...) asparagine
623 N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 4 entries
Pathway Name Organism
Extra-nuclear estrogen signaling Rattus norvegicus
IRS-related events triggered by IGF1R Rattus norvegicus
SHC-related events triggered by IGF1R Rattus norvegicus
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) Rattus norvegicus
Disease
Displaying all 3 entries
DO ID Disease Name Source
DOID:10652 Alzheimer's disease
DOID:14330 Parkinson's disease
DOID:2526 prostate adenocarcinoma
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025