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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Cathepsin D
Summary
- UniProt ID
- P24268
- Gene Symbol
-
- Ctsd
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- 3D-structure
- Aspartyl protease
- Direct protein sequencing
- Disulfide bond
- Glycoprotein
- Lysosome
- Reference proteome
- Secreted
- Signal
- Zymogen
- Gene Ontology (GO)
| GO Term |
|---|
| synaptic vesicle endosomal processing |
| GO Term |
|---|
| extracellular space |
| lysosome |
| melanosome |
| membrane raft |
| presynaptic endosome |
| lysosomal membrane |
| endosome membrane |
| endosome lumen |
| GABA-ergic synapse |
| GO Term |
|---|
| hydrolase activity |
| aspartic-type peptidase activity |
| endopeptidase activity |
| aspartic-type endopeptidase activity |
| peptidase activity |
| peptide binding |
Sequence
MQTPGVLLLILGLLDASSSALIRIPLRKFTSIRRTMTEVGGSVEDLILKGPITKYSMQSSPRTKEPVSELLKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGVVFIAAKFDGILGMGYPFISVNKVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQPGGELMLGGTDSRYYHGELSYLNVTRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLVGPVDEVKELQKAIGAVPLIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTICLSGFMGMDIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKAATL
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 134 | N-linked (GlcNAc...) asparagine | |||
| 255 |
|
|||
| 258 | N-linked (GlcNAc...) asparagine | |||
| 260 |
|
G41247ZX
G80966KZ
G02815KT
G55220VL
G49108TO
G31852PQ
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Collagen degradation | Rattus norvegicus |
| Insulin receptor recycling | Rattus norvegicus |
| MHC class II antigen presentation | Rattus norvegicus |
| Metabolism of Angiotensinogen to Angiotensins | Rattus norvegicus |
| Neutrophil degranulation | Rattus norvegicus |
