Receptor tyrosine-protein kinase let-23

Summary
UniProt ID
P24348
Gene Symbol
  • let-23
  • kin-7
Organism
Caenorhabditis elegans
External Links
GlycoProtDB
GPDB0000498
PubChem
P24348
Annotation
Keyword
  • 3D-structure
  • ATP-binding
  • Cell membrane
  • Developmental protein
  • Disulfide bond
  • Glycoprotein
  • Phosphoprotein
  • Receptor
  • Reference proteome
  • Signal
  • Transmembrane helix
  • Tyrosine-protein kinase
Gene Ontology (GO)
Sequence
MRYPPSIGSILLIIPIFLTFFGNSNAQLWKRCVSPQDCLCSGTTNGISRYGTGNILEDLETMYRGCRRVYGNLEITWIEANEIKKWRESTNSTVDPKNEDSPLKSINFFDNLEEIRGSLIIYRANIQKISFPRLRVIYGDEVFHDNALYIHKNDKVHEVVMRELRVIRNGSVTIQDNPKMCYIGDKIDWKELLYDPDVQKVETTNSHQHCYQNGKSMAKCHESCNDKCWGSGDNDCQRVYRSVCPKSCSQCFYSNSTSSYECCDSACLGGCTGHGPKNCIACSKYELDGICIETCPSRKIFNHKTGRLVFNPDGRYQNGNHCVKECPPELLIENDVCVRHCSDGHHYDATKDVRECEKCRSSSCPKICTVDGHLTNETLKNLEGCEQIDGHLIIEHAFTYEQLKVLETVKIVSEYITIVQQNFYDLKFLKNLQIIEGRKLHNVRWALAIYQCDDLEELSLNSLKLIKTGAVLIMKNHRLCYVSKIDWSSIITSKGKDNKPSLAIAENRDSKLCETEQRVCDKNCNKRGCWGKEPEDCLECKTWKSVGTCVEKCDTKGFLRNQTSMKCERCSPECETCNGLGELDCLTCRHKTLYNSDFGNRMECVHDCPVSHFPTQKNVCEKCHPTCYDNGCTGPDSNLGYGGCKQCKYAVKYENDTIFCLQSSGMNNVCVENDLPNYYISTYDTEGVIETHCEKCSISCKTCSSAGRNVVQNKCVCKHVEYQPNPSERICMDQCPVNSFMVPDTNNTVCKKCHHECDQNYHCANGQSTGCQKCKNFTVFKGDIAQCVSECPKNLPFSNPANGECLDYDIASRQRKTRMVIIGSVLFGFAVMFLFILLVYWRCQRIGKKLKIAEMVDMPELTPIDASVRPNMSRICLIPSSELQTKLDKKLGAGAFGTVFAGIYYPKRAKNVKIPVAIKVFQTDQSQTDEMLEEATNMFRLRHDNLLKIIGFCMHDDGLKIVTIYRPLGNLQNFLKLHKENLGAREQVLYCYQIASGMQYLEKQRVVHRDLATRNVLVKKFNHVEITDFGLSKILKHDADSITIKSGKVAIKWLAIEIFSKHCYTHASDVWAFGVTCWEIITFGQSPYQGMSTDSIHNFLKDGNRLSQPPNCSQDLYQELLRCWMADPKSRPGFEILYERFKEFCKVPQLFLENSNKISESDLSAEERFQTERIREMFDGNIDPQMYFDQGSLPSMPSSPTSMATFTIPHGDLMNRMQSVNSSRYKTEPFDYGSTAQEDNSYLIPKTKEVQQSAVLYTAVTNEDGQTELSPSNGDYYNQPNTPSSSSGYYNEPHLKTKKPETSEEAEAVQYENEEVSQKETCL
Glycosylation Sites
Displaying all 8 entries
Position Description PubMed ID GlyTouCan ID Source
91 N-linked (GlcNAc...) asparagine
169 N-linked (GlcNAc...) asparagine
255 N-linked (GlcNAc...) asparagine
376 N-linked (GlcNAc...) asparagine
561 N-linked (GlcNAc...) asparagine
655 N-linked (GlcNAc...) asparagine
746 N-linked (GlcNAc...) asparagine
776 N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying entries 1 - 10 of 23 in total
Pathway Name Organism
Cargo recognition for clathrin-mediated endocytosis Caenorhabditis elegans
Clathrin-mediated endocytosis Caenorhabditis elegans
Downregulation of ERBB2 signaling Caenorhabditis elegans
Downregulation of ERBB4 signaling Caenorhabditis elegans
Drug-mediated inhibition of ERBB2 signaling Caenorhabditis elegans
EGFR Transactivation by Gastrin Caenorhabditis elegans
EGFR downregulation Caenorhabditis elegans
ERBB2 Activates PTK6 Signaling Caenorhabditis elegans
ERBB2 Regulates Cell Motility Caenorhabditis elegans
Extra-nuclear estrogen signaling Caenorhabditis elegans

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024