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MIRAGE
Collagen alpha-2(VIII) chain

Summary
UniProt ID
P25067
Gene Symbol
  • COL8A2
Gene ID
1296
Organism
Homo sapiens (human)
GlyGen
P25067
The O-GlcNAc Database
P25067
Re-Glyco
P25067
Annotation
Keyword
  • Angiogenesis
  • Basement membrane
  • Cell adhesion
  • Collagen
  • Corneal dystrophy
  • Disease variant
  • Hydroxylation
  • Reference proteome
  • Repeat
  • Signal
Gene Ontology (GO)
Displaying all 7 entries
GO Term
extracellular region
collagen trimer
basement membrane
extracellular space
extracellular matrix
collagen-containing extracellular matrix
endoplasmic reticulum lumen
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Annotation information from UniProt.
Sequence
MLGTLTPLSSLLLLLLVLVLGCGPRASSGGGAGGAAGYAPVKYIQPMQKGPVGPPFREGKGQYLEMPLPLLPMDLKGEPGPPGKPGPRGPPGPPGFPGKPGMGKPGLHGQPGPAGPPGFSRMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSGITIPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNGVGQPGLPGAPGQGGAPGPPGLPGPAGLGKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDGVGVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTGYGMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAGKPGVPGERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPGEGRAGEPGTAGPTGPPGVPGSPGITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNGGVEGAVLGKGGKPQFGLGELSAHATPAFTAVLTSPFPASGMPVKFDRTLYNGHSGYNPATGIFTCPVGGVYYFAYHVHVKGTNVWVALYKNNVPATYTYDEYKKGYLDQASGGAVLQLRPNDQVWVQMPSDQANGLYSTEYIHSSFSGFLLCPT
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 4 entries
Position Description PubMed ID GlyTouCan ID Source
423
432
506
518
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 3 entries
Pathway Name Organism
Assembly of collagen fibrils and other multimeric structures Homo sapiens
Collagen biosynthesis and modifying enzymes Homo sapiens
Collagen chain trimerization Homo sapiens
Disease
Displaying all 2 entries
DO ID Disease Name Source
DOID:0110856 posterior polymorphous corneal dystrophy 2
DOID:11555 Fuchs' endothelial dystrophy
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025