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Guanylyl cyclase C

Summary

UniProt ID

P25092

Gene Symbol

GUCY2C
GUC2C
STAR

Organism

Homo sapiens (human)

External Links

GlyGen: P25092
PubChem: P25092
The Human Metabolome Database: HMDBP01070

Annotation

Keyword

3D-structure
Cell membrane
Disease variant
Endoplasmic reticulum
GTP-binding
Glycoprotein
Lyase
Receptor
Reference proteome
Signal
Transmembrane helix
cGMP biosynthesis

Gene Ontology (GO)

Displaying **all 5** entries
GO Term
cGMP biosynthetic process
receptor guanylyl cyclase signaling pathway
response to toxic substance
regulation of cell population proliferation
intracellular signal transduction

Displaying **all 2** entries
GO Term
endoplasmic reticulum membrane
plasma membrane

Displaying **all 7** entries
GO Term
GTP binding
peptide receptor activity
protein kinase activity
toxic substance binding
adenylate cyclase activity
guanylate cyclase activity
ATP binding

Site Annotations

Displaying 1 entry
Position	Description
357	Not glycosylated

Annotation information from UniProt.

Sequence

MKTLLLDLALWSLLFQPGWLSFSSQVSQNCHNGSYEISVLMMGNSAFAEPLKNLEDAVNEGLEIVRGRLQNAGLNVTVNATFMYSDGLIHNSGDCRSSTCEGLDLLRKISNAQRMGCVLIGPSCTYSTFQMYLDTELSYPMISAGSFGLSCDYKETLTRLMSPARKLMYFLVNFWKTNDLPFKTYSWSTSYVYKNGTETEDCFWYLNALEASVSYFSHELGFKVVLRQDKEFQDILMDHNRKSNVIIMCGGPEFLYKLKGDRAVAEDIVIILVDLFNDQYFEDNVTAPDYMKNVLVLTLSPGNSLLNSSFSRNLSPTKRDFALAYLNGILLFGHMLKIFLENGENITTPKFAHAFRNLTFEGYDGPVTLDDWGDVDSTMVLLYTSVDTKKYKVLLTYDTHVNKTYPVDMSPTFTWKNSKLPNDITGRGPQILMIAVFTLTGAVVLLLLVALLMLRKYRKDYELRQKKWSHIPPENIFPLETNETNHVSLKIDDDKRRDTIQRLRQCKYDKKRVILKDLKHNDGNFTEKQKIELNKLLQIDYYNLTKFYGTVKLDTMIFGVIEYCERGSLREVLNDTISYPDGTFMDWEFKISVLYDIAKGMSYLHSSKTEVHGRLKSTNCVVDSRMVVKITDFGCNSILPPKKDLWTAPEHLRQANISQKGDVYSYGIIAQEIILRKETFYTLSCRDRNEKIFRVENSNGMKPFRPDLFLETAEEKELEVYLLVKNCWEEDPEKRPDFKKIETTLAKIFGLFHDQKNESYMDTLIRRLQLYSRNLEHLVEERTQLYKAERDRADRLNFMLLPRLVVKSLKEKGFVEPELYEEVTIYFSDIVGFTTICKYSTPMEVVDMLNDIYKSFDHIVDHHDVYKVETIGDAYMVASGLPKRNGNRHAIDIAKMALEILSFMGTFELEHLPGLPIWIRIGVHSGPCAAGVVGIKMPRYCLFGDTVNTASRMESTGLPLRIHVSGSTIAILKRTECQFLYEVRGETYLKGRGNETTYWLTGMKDQKFNLPTPPTVENQQRLQAEFSDMIANSLQKRQAAGIRSQKPRRVASYKKGTLEYLQLNTTDKESTYF

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 8** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
32	N-linked (GlcNAc...) asparagine	23269669		UniProt GlyGen
75	N-linked (GlcNAc...) asparagine	23269669		UniProt GlyGen
79	N-linked (GlcNAc...) asparagine	23269669		UniProt GlyGen
195	N-linked (GlcNAc...) asparagine	23269669		UniProt GlyGen
284	N-linked (GlcNAc...) asparagine	23269669		UniProt GlyGen
307	N-linked (GlcNAc...) asparagine	23269669		UniProt GlyGen
345	N-linked (GlcNAc...) asparagine	23269669		UniProt GlyGen
402	N-linked (GlcNAc...) asparagine	23269669	G80920RR	UniProt GlyGen