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MIRAGE
Tyrosine-protein kinase Lyn
Summary
- UniProt ID
- P25911
- Gene Symbol
-
- Lyn
- Gene ID
- 17096
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Adaptive immunity
- Alternative splicing
- Cell membrane
- Cytoplasm
- Golgi apparatus
- Inflammatory response
- Innate immunity
- Myristate
- Nucleus
- Palmitate
- Phosphoprotein
- Proto-oncogene
- Reference proteome
- SH2 domain
- SH3 domain
- Tyrosine-protein kinase
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| nucleus |
| cytoplasm |
| plasma membrane |
| protein-containing complex |
| postsynaptic specialization, intracellular component |
| Golgi apparatus |
| cytosol |
| adherens junction |
| perinuclear region of cytoplasm |
| cytoplasmic side of plasma membrane |
Sequence
MGCIKSKRKDNLNDDEVDSKTQPVRNTDRTIYVRDPTSNKQQRPVPEFHLLPGQRFQTKDPEEQGDIVVALYPYDGIHPDDLSFKKGEKMKVLEEHGEWWKAKSLSSKREGFIPSNYVAKVNTLETEEWFFKDITRKDAERQLLAPGNSAGAFLIRESETLKGSFSLSVRDYDPMHGDVIKHYKIRSLDNGGYYISPRITFPCISDMIKHYQKQSDGLCRRLEKACISPKPQKPWDKDAWEIPRESIKLVKKLGAGQFGEVWMGYYNNSTKVAVKTLKPGTMSVQAFLEEANLMKTLQHDKLVRLYAVVTKEEPIYIITEFMAKGSLLDFLKSDEGGKVLLPKLIDFSAQIAEGMAYIERKNYIHRDLRAANVLVSESLMCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINFGCFTIKSDVWSFGILLYEIVTYGKIPYPGRTNADVMSALSQGYRMPRMENCPDELYDIMKMCWKEKAEERPTFDYLQSVLDDFYTATEGQYQQQP
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 19 |
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Erythropoietin activates Phosphoinositide-3-kinase (PI3K) | Mus musculus |
| Erythropoietin activates RAS | Mus musculus |
| FCERI mediated Ca+2 mobilization | Mus musculus |
| FCERI mediated MAPK activation | Mus musculus |
| FCERI mediated NF-kB activation | Mus musculus |
| FCGR activation | Mus musculus |
| Fc epsilon receptor (FCERI) signaling | Mus musculus |
| GPVI-mediated activation cascade | Mus musculus |
| Growth hormone receptor signaling | Mus musculus |
| Inactivation of CSF3 (G-CSF) signaling | Mus musculus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:9074 | systemic lupus erythematosus |
