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Transforming growth factor beta receptor type 3

Summary

UniProt ID

P26342

Gene Symbol

Tgfbr3

Organism

Rattus norvegicus (Norway rat)

External Links

GlyGen: P26342
PubChem: P26342

Annotation

Keyword

3D-structure
Cell membrane
Direct protein sequencing
Disulfide bond
Extracellular matrix
Proteoglycan
Receptor
Reference proteome
Signal
Transmembrane helix

Gene Ontology (GO)

Displaying entries **41 - 50** of 57 in total

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GO Term
secondary palate development
regulation of transforming growth factor beta receptor signaling pathway
positive regulation of transforming growth factor beta receptor signaling pathway
negative regulation of transforming growth factor beta receptor signaling pathway
positive regulation of BMP signaling pathway
response to hypoxia
negative regulation of canonical NF-kappaB signal transduction
ventricular compact myocardium morphogenesis
transforming growth factor beta receptor signaling pathway
BMP signaling pathway

Displaying **all 9** entries
GO Term
extracellular space
cytoplasm
membrane
collagen-containing extracellular matrix
receptor complex
endoplasmic reticulum
external side of plasma membrane
cell surface
inhibin-betaglycan-ActRII complex

Displaying entries **1 - 10** of 14 in total

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GO Term
transmembrane signaling receptor activity
glycosaminoglycan binding
heparin binding
PDZ domain binding
activin binding
SMAD binding
fibroblast growth factor binding
transforming growth factor beta receptor activity
type II transforming growth factor beta receptor binding
transforming growth factor beta receptor binding

Annotation information from UniProt.

Sequence

MAVTSHHMIPVMVVLMSACLATAGPEPSTRCELSPINASHPVQALMESFTVLSGCASRGTTGLPREVHVLNLRSTDQGPGQRQREVTLHLNPIASVHTHHKPIVFLLNSPQPLVWHLKTERLAAGVPRLFLVSEGSVVQFPSGNFSLTAETEERNFPQENEHLLRWAQKEYGAVTSFTELKIARNIYIKVGEDQVFPPTCNIGKNFLSLNYLAEYLQPKAAEGCVLPSQPHEKEVHIIELITPSSNPYSAFQVDIIVDIRPAQEDPEVVKNLVLILKCKKSVNWVIKSFDVKGNLKVIAPNSIGFGKESERSMTMTKLVRDDIPSTQENLMKWALDNGYRPVTSYTMAPVANRFHLRLENNEEMRDEEVHTIPPELRILLDPDHPPALDNPLFPGEGSPNGGLPFPFPDIPRRGWKEGEDRIPRPKQPIVPSVQLLPDHREPEEVQGGVDIALSVKCDHEKMVVAVDKDSFQTNGYSGMELTLLDPSCKAKMNGTHFVLESPLNGCGTRHRRSTPDGVVYYNSIVVQAPSPGDSSGWPDGYEDLESGDNGFPGDGDEGETAPLSRAGVVVFNCSLRQLRNPSGFQGQLDGNATFNMELYNTDLFLVPSPGVFSVAENEHVYVEVSVTKADQDLGFAIQTCFLSPYSNPDRMSDYTIIENICPKDDSVKFYSSKRVHFPIPHAEVDKKRFSFLFKSVFNTSLLFLHCELTLCSRKKGSLKLPRCVTPDDACTSLDATMIWTMMQNKKTFTKPLAVVLQVDYKENVPSTKDSSPIPPPPPQIFHGLDTLTVMGIAFAAFVIGALLTGALWYIYSHTGETARRQQVPTSPPASENSSAAHSIGSTQSTPCSSSSTA

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 8** entries
Position	Description	PubMed ID	Source
37	N-linked (GlcNAc...) asparagine		UniProt GlyGen
144	N-linked (GlcNAc...) asparagine		UniProt GlyGen
493	N-linked (GlcNAc...) asparagine		UniProt GlyGen
535	O-linked (Xyl...) (glycosaminoglycan) serine		UniProt GlyGen
546	O-linked (Xyl...) (glycosaminoglycan) serine		UniProt GlyGen
572	N-linked (GlcNAc...) asparagine		UniProt GlyGen
591	N-linked (GlcNAc...) asparagine	21402931	UniProt GlyGen
698	N-linked (GlcNAc...) asparagine	21402931	UniProt GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 5** entries
Pathway Name	Organism
FGFR1b ligand binding and activation	Rattus norvegicus
FGFR1c ligand binding and activation	Rattus norvegicus
Signaling by Activin	Rattus norvegicus
Signaling by BMP	Rattus norvegicus
TGF-beta receptor signaling activates SMADs	Rattus norvegicus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

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Summary

External Links

Annotation

International Collaboration

Acknowledgements