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Proteinase-activated receptor 1

Summary

UniProt ID

P26824

Gene Symbol

F2r
Par1

Organism

Rattus norvegicus (Norway rat)

External Links

PubChem: P26824

Annotation

Keyword

Blood coagulation
Cell membrane
Disulfide bond
G-protein coupled receptor
Glycoprotein
Phosphoprotein
Reference proteome
Signal
Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 10** of 42 in total

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GO Term
positive regulation of interleukin-6 production
positive regulation of interleukin-8 production
positive regulation of collagen biosynthetic process
dendritic cell homeostasis
negative regulation of neuron apoptotic process
positive regulation of smooth muscle contraction
homeostasis of number of cells within a tissue
positive regulation of calcium ion transport
negative regulation of renin secretion into blood stream
phospholipase C-activating G protein-coupled receptor signaling pathway

Displaying **all 8** entries
GO Term
platelet dense tubular network
caveola
early endosome
late endosome
plasma membrane
neuromuscular junction
postsynaptic membrane
cell surface

Displaying **all 5** entries
GO Term
G protein-coupled receptor activity
signaling receptor binding
G-protein beta-subunit binding
G-protein alpha-subunit binding
thrombin-activated receptor activity

Annotation information from UniProt.

Sequence

MGPRRLLLVAVGLSLCGPLLSSRVPMRQPESERMYATPYATPNPRSFFLRNPSEDTFEQFPLGDEEEKNESIPLEGRAVYLNKSRFPPMPPPPFISEDASGYLTSPWLTLFIPSVYTFVFIVSLPLNILAIAVFVFRMKVKKPAVVYMLHLAMADVLFVSVLPFKISYYFSGTDWQFGSGMCRFATAACYCNMYASIMLMTVISIDRFLAVVYPIQSLSWRTLGRANFTCVVIWVMAIMGVVPLLLKEQTTQVPGLNITTCHDVLNETLLHGFYSYYFSAFSAIFFLVPLIISTVCYTSIIRCLSSSAVANRSKKSRALFLSAAVFCIFIVCFGPTNVLLIVHYLLLSDSPGTETAYFAYLLCVCVTSVASCIDPLIYYYASSECQKHLYSILCCRESSDSNSCNSTGQLMPSKMDTCSSHLNNSIYKKLLA

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 4** entries
Position	Description	Source
69	N-linked (GlcNAc...) asparagine	UniProt
82	N-linked (GlcNAc...) asparagine	UniProt
257	N-linked (GlcNAc...) asparagine	UniProt
266	N-linked (GlcNAc...) asparagine	UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 4** entries
Pathway Name	Organism
Common Pathway of Fibrin Clot Formation	Rattus norvegicus
G alpha (q) signalling events	Rattus norvegicus
Peptide ligand-binding receptors	Rattus norvegicus
Thrombin signalling through proteinase activated receptors (PARs)	Rattus norvegicus