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MIRAGE
Properdin
Summary
- UniProt ID
- P27918
- Gene Symbol
-
- CFP
- PFC
- Gene ID
- 5199
- Organism
- Homo sapiens (human)
External Links
- GlycoProtDB
- GPDB0011643
- GlyGen
- P27918
- PubChem
- P27918
- Re-Glyco
- P27918
Annotation
- Keyword
-
- 3D-structure
- Complement alternate pathway
- Disease variant
- Disulfide bond
- Glycoprotein
- Reference proteome
- Repeat
- Secreted
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| extracellular region |
| extracellular space |
| specific granule lumen |
| cytoplasmic side of Golgi membrane |
| tertiary granule lumen |
| endoplasmic reticulum lumen |
Sequence
MITEGAQAPRLLLPPLLLLLTLPATGSDPVLCFTQYEESSGKCKGLLGGGVSVEDCCLNTAFAYQKRSGGLCQPCRSPRWSLWSTWAPCSVTCSEGSQLRYRRCVGWNGQCSGKVAPGTLEWQLQACEDQQCCPEMGGWSGWGPWEPCSVTCSKGTRTRRRACNHPAPKCGGHCPGQAQESEACDTQQVCPTHGAWATWGPWTPCSASCHGGPHEPKETRSRKCSAPEPSQKPPGKPCPGLAYEQRRCTGLPPCPVAGGWGPWGPVSPCPVTCGLGQTMEQRTCNHPVPQHGGPFCAGDATRTHICNTAVPCPVDGEWDSWGEWSPCIRRNMKSISCQEIPGQQSRGRTCRGRKFDGHRCAGQQQDIRHCYSIQHCPLKGSWSEWSTWGLCMPPCGPNPTRARQRLCTPLLPKYPPTVSMVEGQGEKNVTFWGRPLPRCEELQGQKLVVEEKRPCLHVPACKDPEEEEL
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 83 | C-linked (Man) tryptophan |
|
||
| 86 | C-linked (Man) tryptophan |
|
||
| 92 | O-linked (Fuc...) threonine |
|
||
| 139 | C-linked (Man) tryptophan |
|
||
| 142 | C-linked (Man) tryptophan |
|
||
| 145 | C-linked (Man) tryptophan |
|
||
| 151 | O-linked (Fuc...) threonine |
|
||
| 196 | C-linked (Man) tryptophan |
|
||
| 199 | C-linked (Man) tryptophan |
|
||
| 202 | C-linked (Man) tryptophan |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Defective B3GALTL causes PpS | Homo sapiens |
| Neutrophil degranulation | Homo sapiens |
| O-glycosylation of TSR domain-containing proteins | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0111768 | X-linked properdin deficiency |
