Progranulin
| GO Term |
|---|
| extracellular region |
| extracellular space |
| lysosome |
| plasma membrane |
| membrane |
| endosome |
| late endosome |
| endoplasmic reticulum |
| Golgi apparatus |
| trans-Golgi network |
| GO Term |
|---|
| RNA binding |
| cytokine activity |
| growth factor activity |
| protein-folding chaperone binding |
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 537 |
|
|
| Pathway Name | Organism |
|---|---|
| Neutrophil degranulation | Homo sapiens |
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050784 | primary progressive multiple sclerosis | |
| DOID:0060672 | Grn-related frontotemporal lobar degeneration with Tdp43 inclusions | |
| DOID:0110732 | neuronal ceroid lipofuscinosis 11 | |
| DOID:10652 | Alzheimer's disease | |
| DOID:1307 | dementia | |
| DOID:332 | amyotrophic lateral sclerosis | |
| DOID:9255 | frontotemporal dementia |
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Supported by JST NBDC Grant Number JPMJND2204
Partly supported by NIH Common Fund Grant #1U01GM125267-01
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Last updated: December 8, 2025