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MIRAGE
Proprotein convertase subtilisin/kexin type 4
Summary
- UniProt ID
- P29121
- Gene Symbol
-
- Nec-3
- Nec3
- Pcsk4
- Gene ID
- 18551
- Organism
- Mus musculus (house mouse)
External Links
- Re-Glyco
- P29121
Annotation
- Keyword
-
- Alternative splicing
- Cleavage on pair of basic residues
- Cytoplasmic vesicle
- Glycoprotein
- Membrane
- Reference proteome
- Serine protease
- Signal
- Zymogen
- Gene Ontology (GO)
| GO Term |
|---|
| endoplasmic reticulum lumen |
| acrosomal vesicle |
| acrosomal membrane |
| GO Term |
|---|
| binding of sperm to zona pellucida |
| acrosome reaction |
| fertilization |
| protein processing |
| reproductive process |
| sperm capacitation |
| GO Term |
|---|
| serine-type endopeptidase activity |
Sequence
MRPSQTELWLGLTLTLALLAVRWASAQAPIYVSSWAVRVTKGYQEAERLARKFGFVNLGQIFPDDQYFHLRHRGVAQQSLTPHWGHRLRLKKDPKVRWFEQQTLRRRVKRSLVVPTDPWFSKQWYMNKEIQQDLNILKAWNQGLTGRGVVISILDDGIEKDHPDLWANYDPLASYDFNDYDPDPQPRYTPNDENRHGTRCAGEVSATANNGFCGAGVAFNARIGGVRMLDGAITDIVEAQSLSLQPQHIHIYSASWGPEDDGRTVDGPGLLTQEAFRRGVTKGRQGLGTLFIWASGNGGLHYDNCNCDGYTNSIHTLSVGSTTRQGRVPWYSEACASTFTTTFSSGVVTDPQIVTTDLHHQCTDKHTGTSASAPLAAGMIALALEANPLLTWRDLQHLVVRASRPAQLQAEDWRINGVGRQVSHHYGYGLLDAGLLVDLARVWLPTKPQKKCAIRVVHTPTPILPRMLVPKNVTACSDGSRRRLIRSLEHVQVQLSLSYSRRGDLEIFLTSPMGTRSTLVAIRPLDISGQGYNNWIFMSTHYWDEDPQGLWTLGLENKGYYFNTGTLYYYTLLLYGTAEDMTARPQAPQVTSRARACVQRDTEGLCQESHSPLSILAGLCLISSQQWWWLYSHPQQPVTEGQASCHPPVTPAAAA
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 472 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
