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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Tyrosine-protein phosphatase non-receptor type 6
Summary
- UniProt ID
- P29350
- Gene Symbol
-
- PTPN6
- HCP
- PTP1C
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cytoplasm
- Nucleus
- Phosphoprotein
- Protein phosphatase
- Reference proteome
- Repeat
- SH2 domain
- Gene Ontology (GO)
| GO Term |
|---|
| regulation of type I interferon-mediated signaling pathway |
| GO Term |
|---|
| nucleoplasm |
| cytosol |
| extracellular region |
| nucleus |
| nucleolus |
| cytoplasm |
| plasma membrane |
| cell-cell junction |
| membrane |
| protein-containing complex |
Sequence
MVRWFHRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQNSGDFYDLYGGEKFATLTELVEYYTQQQGVLQDRDGTIIHLKYPLNCSDPTSERWYHGHMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPLRVTHIKVMCEGGRYTVGGLETFDSLTDLVEHFKKTGIEEASGAFVYLRQPYYATRVNAADIENRVLELNKKQESEDTAKAGFWEEFESLQKQEVKNLHQRLEGQRPENKGKNRYKNILPFDHSRVILQGRDSNIPGSDYINANYIKNQLLGPDENAKTYIASQGCLEATVNDFWQMAWQENSRVIVMTTREVEKGRNKCVPYWPEVGMQRAYGPYSVTNCGEHDTTEYKLRTLQVSPLDNGDLIREIWHYQYLSWPDHGVPSEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVIDMLMENISTKGLDCDIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEVLQSQKGQESEYGNITYPPAMKNAHAKASRTSSKHKEDVYENLHTKNKREEKVKKQRSADKEKSKGSLKRK
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 151 |
|
|||
| 250 |
|
|||
| 350 |
|
G49108TO
G70994MS
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Neutrophil degranulation | Homo sapiens |
| Nuclear events stimulated by ALK signaling in cancer | Homo sapiens |
| PD-1 signaling | Homo sapiens |
| PECAM1 interactions | Homo sapiens |
| Platelet sensitization by LDL | Homo sapiens |
| Regulation of IFNA/IFNB signaling | Homo sapiens |
| Regulation of IFNG signaling | Homo sapiens |
| Regulation of KIT signaling | Homo sapiens |
| SARS-CoV-2 activates/modulates innate and adaptive immune responses | Homo sapiens |
| Signal regulatory protein family interactions | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
