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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Transketolase
Summary
- UniProt ID
- P29401
- Gene Symbol
-
- TKT
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Alternative splicing
- Calcium
- Direct protein sequencing
- Disease variant
- Dwarfism
- Isopeptide bond
- Magnesium
- Metal-binding
- Phosphoprotein
- Reference proteome
- Thiamine pyrophosphate
- Transferase
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| vesicle |
| nuclear body |
| extracellular exosome |
| peroxisome |
| cytosol |
| nucleoplasm |
| endoplasmic reticulum membrane |
| GO Term |
|---|
| calcium ion binding |
| thiamine pyrophosphate binding |
| protein homodimerization activity |
| magnesium ion binding |
| transketolase activity |
Sequence
MESYHKPDQQKLQALKDTANRLRISSIQATTAAGSGHPTSCCSAAEIMAVLFFHTMRYKSQDPRNPHNDRFVLSKGHAAPILYAVWAEAGFLAEAELLNLRKISSDLDGHPVPKQAFTDVATGSLGQGLGAACGMAYTGKYFDKASYRVYCLLGDGELSEGSVWEAMAFASIYKLDNLVAILDINRLGQSDPAPLQHQMDIYQKRCEAFGWHAIIVDGHSVEELCKAFGQAKHQPTAIIAKTFKGRGITGVEDKESWHGKPLPKNMAEQIIQEIYSQIQSKKKILATPPQEDAPSVDIANIRMPSLPSYKVGDKIATRKAYGQALAKLGHASDRIIALDGDTKNSTFSEIFKKEHPDRFIECYIAEQNMVSIAVGCATRNRTVPFCSTFAAFFTRAFDQIRMAAISESNINLCGSHCGVSIGEDGPSQMALEDLAMFRSVPTSTVFYPSDGVATEKAVELAANTKGICFIRTSRPENAIIYNNNEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAELLKKEKINIRVLDPFTIKPLDRKLILDSARATKGRILTVEDHYYEGGIGEAVSSAVVGEPGITVTHLAVNRVPRSGKPAELLKMFGIDRDAIAQAVRGLITKA
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 344 |
|
|||
| 345 |
|
G83460ZZ
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Insulin effects increased synthesis of Xylulose-5-Phosphate | Homo sapiens |
| NFE2L2 regulates pentose phosphate pathway genes | Homo sapiens |
| Pentose phosphate pathway | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:409 | liver disease | |
| DOID:0050589 | inflammatory bowel disease | |
| DOID:0050741 | alcohol dependence | |
| DOID:0060192 | Crohn's colitis | |
| DOID:0060262 | gallbladder disease | |
| DOID:0060891 | Parkinson's disease 19A | |
| DOID:0060895 | Parkinson's disease 4 | |
| DOID:0060896 | Parkinson's disease 23 | |
| DOID:0070313 | thiamine deficiency disease | |
| DOID:0070318 | dry beriberi |
