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Macrophage scavenger receptor types I and II

Summary

UniProt ID

P30204

Gene Symbol

Msr1
Scvr

Gene ID

20288

Organism

Mus musculus (house mouse)

External Links

GlycoProtDB: GPDB0003551
GlyGen: P30204
PubChem: P30204
The O-GlcNAc Database: P30204
RaftProt: P30204
Re-Glyco: P30204

Annotation

Keyword

3D-structure
Alternative splicing
Coiled coil
Collagen
Disulfide bond
Endocytosis
Glycoprotein
LDL
Phosphoprotein
Receptor
Reference proteome
Signal-anchor
Transmembrane helix

Gene Ontology (GO)

Displaying **all 3** entries
GO Term
collagen trimer
plasma membrane
low-density lipoprotein particle

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying **all 10** entries
GO Term
plasma lipoprotein particle clearance
receptor-mediated endocytosis
cholesterol transport
lipoprotein transport
phagocytosis, engulfment
positive regulation of macrophage derived foam cell differentiation
positive regulation of cholesterol storage
negative regulation of gene expression
establishment of localization in cell
amyloid-beta clearance

Displaying **all 4** entries
GO Term
low-density lipoprotein particle binding
amyloid-beta binding
scavenger receptor activity
cargo receptor activity

Annotation information from UniProt.

Sequence

MTKEMTENQRLCPHEQEDADCSSESVKFDARSMTASLPHSTKNGPSLQEKLKSFKAALIALYLLVFAVLIPVVGIVTAQLLNWEMKNCLVCSLNTSDTSQGPMEKENTSKVEMRFTIIMEHMKDMEERIESISNSKADLIDTERFQNFSMATDQRLNDILLQLNSLISSVQEHGNSLDAISKSLQSLNMTLLDVQLHTETLNVRVRESTAKQQEDISKLEERVYKVSAEVQSVKEEQAHVEQEVKQEVRVLNNITNDLRLKDWEHSQTLKNITFIQGPPGPQGEKGDRGLTGQTGPPGAPGIRGIPGVKGDRGQIGFPGGRGNPGAPGKPGRSGSPGPKGQKGEKGSVGGSTPLKTVRLVGGSGAHEGRVEIFHQGQWGTICDDRWDIRAGQVVCRSLGYQEVLAVHKRAHFGQGTGPIWLNEVMCFGRESSIENCKINQWGVLSCSHSEDAGVTCTS

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 7** entries
Position	Description	GlyTouCan ID	Source
94	N-linked (GlcNAc...) asparagine		GlycoProtDB UniProt GlyGen
107	N-linked (GlcNAc...) asparagine		GlycoProtDB UniProt GlyGen
147	N-linked (GlcNAc...) asparagine	G86182NS	GlycoProtDB UniProt GlyGen
188	N-linked (GlcNAc...) asparagine	G62765YT	GlycoProtDB UniProt GlyGen
253	N-linked (GlcNAc...) asparagine		GlycoProtDB UniProt GlyGen
271	N-linked (GlcNAc...) asparagine	G02815KT	UniProt GlyGen
351		G49108TO	The O-GlcNAc Database