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Cyclin-dependent kinase 4

Summary

UniProt ID

P30285

Gene Symbol

Cdk4
Crk3

Organism

Mus musculus (house mouse)

External Links

GlyGen: P30285
PubChem: P30285
The O-GlcNAc Database: P30285

Annotation

Keyword

ATP-binding
Acetylation
Cell division
Cytoplasm
Membrane
Nucleus
Phosphoprotein
Proto-oncogene
Reference proteome
Serine/threonine-protein kinase

Gene Ontology (GO)

Displaying entries **11 - 20** of 23 in total

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GO Term
positive regulation of translation
positive regulation of fibroblast proliferation
regulation of type B pancreatic cell proliferation
cellular response to lipopolysaccharide
positive regulation of cell size
response to xenobiotic stimulus
G1/S transition of mitotic cell cycle
response to lead ion
regulation of G2/M transition of mitotic cell cycle
positive regulation of G2/M transition of mitotic cell cycle

Displaying entries **1 - 10** of 14 in total

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GO Term
cytosol
cyclin-dependent protein kinase holoenzyme complex
nucleoplasm
transcription regulator complex
perinuclear region of cytoplasm
cyclin D1-CDK4 complex
cyclin D2-CDK4 complex
cyclin D3-CDK4 complex
chromatin
nucleus

Displaying **all 7** entries
GO Term
protein kinase activity
kinase activity
protein-containing complex binding
cyclin binding
cyclin-dependent protein serine/threonine kinase activity
ATP binding
protein serine kinase activity

Annotation information from UniProt.

Sequence

MAATRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGAAGGGLPVSTVREVALLRRLEAFEHPNVVRLMDVCATSRTDRDIKVTLVFEHIDQDLRTYLDKAPPPGLPVETIKDLMRQFLSGLDFLHANCIVHRDLKPENILVTSNGTVKLADFGLARIYSYQMALTPVVVTLWYRAPEVLLQSTYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDDWPREVSLPRGAFAPRGPRPVQSVVPEMEESGAQLLLEMLTFNPHKRISAFRALQHSYLHKEESDAE

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites