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MIRAGE
Neuronal acetylcholine receptor subunit beta-4

Summary
UniProt ID
P30926
Gene Symbol
CHRNB4
Gene ID
1143
Organism
Homo sapiens (human)
PubChem
P30926
The Human Metabolome Database
HMDBP12046
Re-Glyco
P30926
Annotation
Keyword
3D-structure Alternative splicing Cell membrane Disulfide bond Glycoprotein Ligand-gated ion channel Proteomics identification Receptor Reference proteome Signal Synapse Transmembrane helix
Gene Ontology (GO)
Displaying entries 1 - 5 of 25 in total
GO Term Evidence Code Reference
ion transport
monoatomic ion transport
ion transport
monoatomic ion transport
smooth muscle contraction
GO Hierarchy
Displaying entries 1 - 5 of 23 in total
GO Term Evidence Code Reference
plasma membrane
plasma membrane
plasma membrane
plasma membrane
plasma membrane
GO Hierarchy
Displaying entries 1 - 5 of 8 in total
GO Term Evidence Code Reference
ligand-gated monoatomic ion channel activity
acetylcholine receptor activity
acetylcholine receptor activity
acetylcholine receptor activity
acetylcholine-gated monoatomic cation-selective channel activity
GO Hierarchy
Gene Ontology information from UniProt.
Annotation information from UniProt.
Sequence
MRRAPSLVLFFLVALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVLMTPTASMDDFTPSGEWDIVALPGRRTVNPQDPSYVDVTYDFIIKRKPLFYTINLIIPCVLTTLLAILVFYLPSDCGEKMTLCISVLLALTFFLLLISKIVPPTSLDVPLIGKYLMFTMVLVTFSIVTSVCVLNVHHRSPSTHTMAPWVKRCFLHKLPTFLFMKRPGPDSSPARAFPPSKSCVTKPEATATSTSPSNFYGNSMYFVNPASAASKSPAGSTPVAIPRDFWLRSSGRFRQDVQEALEGVSFIAQHMKNDDEDQSVVEDWKYVAMVVDRLFLWVFMFVCVLGTVGLFLPPLFQTHAASEGPYAAQRD
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 4 entries
Position Description PubMed ID GlyTouCan ID Source
36
  • N-linked (GlcNAc...) asparagine
93
  • N-linked (GlcNAc...) asparagine
138
  • N-linked (GlcNAc...) asparagine
166
  • N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 4 entries
Pathway Name Organism
Highly calcium permeable nicotinic acetylcholine receptors Homo sapiens
Highly calcium permeable postsynaptic nicotinic acetylcholine receptors Homo sapiens
Highly sodium permeable postsynaptic acetylcholine nicotinic receptors Homo sapiens
Neutrophil degranulation Homo sapiens
Disease
Displaying all 7 entries
DO ID Disease Name Source
DOID:3907 lung squamous cell carcinoma
DOID:1324 lung cancer
DOID:3908 lung non-small cell carcinoma
DOID:3910 lung adenocarcinoma
DOID:0050742 nicotine dependence
DOID:8618 oral cavity cancer
DOID:809 cocaine abuse
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 6, 2026