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Gamma-aminobutyric acid receptor subunit alpha-5

Summary

UniProt ID

P31644

Gene Symbol

GABRA5

Organism

Homo sapiens (human)

External Links

GlyGen: P31644
PubChem: P31644
The Human Metabolome Database: HMDBP08202
The O-GlcNAc Database: P31644

Annotation

Keyword

3D-structure
Cell membrane
Chloride channel
Disease variant
Disulfide bond
Epilepsy
Glycoprotein
Isopeptide bond
Ligand-gated ion channel
Postsynaptic cell membrane
Receptor
Reference proteome
Signal
Transmembrane helix
Ubl conjugation

Gene Ontology (GO)

Displaying entries **1 - 10** of 11 in total

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GO Term
signal transduction
gamma-aminobutyric acid signaling pathway
synaptic transmission, GABAergic
regulation of postsynaptic membrane potential
inner ear receptor cell development
cochlea development
innervation
chloride transmembrane transport
behavioral fear response
associative learning

Displaying entries **1 - 10** of 14 in total

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GO Term
postsynapse
GABA-ergic synapse
transmembrane transporter complex
chloride channel complex
cytosol
nucleoplasm
neuronal cell body membrane
presynaptic membrane
postsynaptic specialization membrane
GABA-A receptor complex

Displaying **all 8** entries
GO Term
transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
GABA-gated chloride ion channel activity
GABA receptor binding
GABA-A receptor activity
inhibitory extracellular ligand-gated monoatomic ion channel activity
benzodiazepine receptor activity
signaling receptor activity
ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential

Annotation information from UniProt.

Sequence

MDNGMFSGFIMIKNLLLFCISMNLSSHFGFSQMPTSSVKDETNDNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQSWKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLYTMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVVAEDGSRLNQYHLMGQTVGTENISTSTGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKKALEAAKIKKKREVILNKSTNAFTTGKMSHPPNIPKEQTPAGTSNTTSVSVKPSEEKTSESKKTYNSISKIDKMSRIVFPVLFGTFNLVYWATYLNREPVIKGAASPK

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 5** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
45	N-linked (GlcNAc...) asparagine			UniProt GlyGen
145	N-linked (GlcNAc...) asparagine	30140029		UniProt GlyGen
207	N-linked (GlcNAc...) asparagine			UniProt GlyGen
236	N-linked (GlcNAc...) asparagine	30140029		UniProt GlyGen
			G49108TO	GlyGen The O-GlcNAc Database