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RAC-alpha serine/threonine-protein kinase
Summary
- UniProt ID
- P31750
- Gene Symbol
-
- Akt
- Akt1
- Rac
- Gene ID
- 11651
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- ATP-binding
- Acetylation
- Apoptosis
- Cell membrane
- Cytoplasm
- Developmental protein
- Disulfide bond
- Glucose metabolism
- Glycogen biosynthesis
- Glycogen metabolism
- Glycoprotein
- Isopeptide bond
- Mitochondrion
- Neurogenesis
- Nucleus
- Phosphoprotein
- Reference proteome
- Serine/threonine-protein kinase
- Sugar transport
- Translation regulation
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| nucleus |
| cytoplasm |
| mitochondrion |
| plasma membrane |
| cell-cell junction |
| vesicle |
| protein-containing complex |
| glutamatergic synapse |
| nucleoplasm |
| cytosol |
Sequence
MNDVAIVKEGWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERPQDVDQRESPLNNFSVAQCQLMKTERPRPNTFIIRCLQWTTVIERTFHVETPEEREEWATAIQTVADGLKRQEEETMDFRSGSPSDNSGAEEMEVSLAKPKHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKSLLSGLLKKDPTQRLGGGSEDAKEIMQHRFFANIVWQDVYEKKLSPPFKPQVTSETDTRYFDEEFTAQMITITPPDQDDSMECVDSERRPHFPQFSYSASGTA
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 126 | O-linked (GlcNAc) serine; alternate |
|
||
| 129 | O-linked (GlcNAc) serine; alternate |
|
||
| 305 | O-linked (GlcNAc) threonine |
|
||
| 308 |
|
|||
| 312 | O-linked (GlcNAc) threonine |
|
||
| 430 |
|
|||
| 473 | O-linked (GlcNAc) serine; alternate |
|
||
| 479 |
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Estrogen-dependent nuclear events downstream of ESR-membrane signaling | Mus musculus |
| Extra-nuclear estrogen signaling | Mus musculus |
| FLT3 Signaling | Mus musculus |
| G beta:gamma signalling through PI3Kgamma | Mus musculus |
| High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells | Mus musculus |
| Integrin signaling | Mus musculus |
| KEAP1-NFE2L2 pathway | Mus musculus |
| KSRP (KHSRP) binds and destabilizes mRNA | Mus musculus |
| MTOR signalling | Mus musculus |
| Mitochondrial unfolded protein response (UPRmt) | Mus musculus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:13482 | Proteus syndrome | |
| DOID:5419 | schizophrenia |
