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Amphiregulin

Summary

UniProt ID

P31955

Gene Symbol

Areg
Sdgf

Organism

Mus musculus (house mouse)

External Links

PubChem: P31955

Annotation

Keyword

Cytokine
Disulfide bond
EGF-like domain
Glycoprotein
Growth factor
Reference proteome
Signal
Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 10** of 18 in total

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GO Term
ERBB2-EGFR signaling pathway
response to hydrogen peroxide
glial cell proliferation
neuron projection development
response to estradiol
response to peptide hormone
negative regulation of osteoblast differentiation
positive regulation of peptidyl-tyrosine phosphorylation
response to glucocorticoid
mammary gland alveolus development

Displaying **all 5** entries
GO Term
extracellular space
nucleus
cytoplasm
membrane
cell surface

Displaying **all 5** entries
GO Term
transmembrane receptor protein tyrosine kinase activator activity
cytokine activity
receptor ligand activity
epidermal growth factor receptor binding
growth factor activity

Annotation information from UniProt.

Sequence

MRTPLLPLARSVLLLLVLGSGHYAAALELNDPSSGKGESLSGDHSAGGLELSVGREVSTISEMPSGSELSTGDYDYSEEYDNEPQISGYIIDDSVRVEQVIKPKKNKTEGEKSTEKPKRKKKGGKNGKGRRNKKKKNPCTAKFQNFCIHGECRYIENLEVVTCNCHQDYFGERCGEKSMKTHSEDDKDLSKIAVVAVTIFVSAIILAAIGIGIVITVHLWKRYFREYEGETEERRRLRQENGTVHAIA

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
106	N-linked (GlcNAc...) asparagine			UniProt
241	N-linked (GlcNAc...) asparagine			UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying entries **11 - 14** of 14 in total

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Pathway Name	Organism
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling	Mus musculus
RAF/MAP kinase cascade	Mus musculus
SHC1 events in EGFR signaling	Mus musculus
Signaling by EGFR	Mus musculus