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Aquaporin-2
Summary
- UniProt ID
- P34080
- Gene Symbol
-
- Aqp2
- Gene ID
- 25386
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- Cell membrane
- Cytoplasmic vesicle
- Glycoprotein
- Golgi apparatus
- Phosphoprotein
- Reference proteome
- Repeat
- Transmembrane helix
- Transport
- Gene Ontology (GO)
| GO Term |
|---|
| plasma membrane |
| membrane |
| cytoplasmic vesicle membrane |
| cytoplasmic vesicle |
| protein-containing complex |
| early endosome |
| trans-Golgi network |
| basolateral plasma membrane |
| apical plasma membrane |
| clathrin-coated vesicle |
| GO Term |
|---|
| actin binding |
| water channel activity |
| water transmembrane transporter activity |
| PDZ domain binding |
| glycerol transmembrane transporter activity |
Sequence
MWELRSIAFSRAVLAEFLATLLFVFFGLGSALQWASSPPSVLQIAVAFGLGIGILVQALGHVSGAHINPAVTVACLVGCHVSFLRAAFYVAAQLLGAVAGAAILHEITPVEIRGDLAVNALHNNATAGQAVTVELFLTMQLVLCIFASTDERRGDNLGSPALSIGFSVTLGHLLGIYFTGCSMNPARSLAPAVVTGKFDDHWVFWIGPLVGAIIGSLLYNYLLFPSAKSLQERLAVLKGLEPDTDWEEREVRRRQSVELHSPQSLPRGSKA
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 124 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Passive transport by Aquaporins | Rattus norvegicus |
| Vasopressin regulates renal water homeostasis via Aquaporins | Rattus norvegicus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:9409 | diabetes insipidus |
