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MIRAGE
NPC intracellular cholesterol transporter 1 homolog 2

Summary
UniProt ID
P34389
Gene Symbol
  • F09G8.4
  • ncr-2
  • npc-2
Gene ID
176165
Organism
Caenorhabditis elegans
PubChem
P34389
Re-Glyco
P34389
Annotation
Keyword
  • Developmental protein
  • Disulfide bond
  • Glycoprotein
  • Lipid transport
  • Reference proteome
  • Signal
  • Transmembrane helix
Gene Ontology (GO)
Displaying 1 entry
GO Term
plasma membrane
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying 1 entry
GO Term
cholesterol binding
Annotation information from UniProt.
Sequence
MRQGGGGGERMVSVLFLLLIHLALCQAKCVMTECDGEEDSNHPPCKTNKSTYLPITVTRSLNPTYMARFEKYCSYLVQEEDKAQVCCTELQLKGMTDRISNAATILGSCPSCFDNFAKLWCQFTCSPDQSKFMKVMETTGPKNVVVKMEFKVNRDFVEGLYESCRHTWFANGLALRLMSLGGKVSFENFYGFMGTKNLAQSIPINTEFQFSRMKNAMNIPTTPCHKSAGPKVPACGAIDCPTNAHQLVDISKVEHLGTKVFHPHFPDFEWLLKICGCLALTVLLVFILKYSCHRRSAPNGEDGCYVDLGKGNLEVQFEGLCARYANAVIKHPLIFVSLGLIVAAACCSGNFKFHSLTHSVDQVSAADGETRRNEKKFIHSFGPNHRIEQIFINLPPTTKSMFNMPLFEEMFQLVGNIQNLTACYGNSSVKLDDICYKPIGKNHGCAIMSPTNYFQNKWTNFENAGPPTIDDEIFDDQHWEHLKYCIRNPLTVSTYSEMSCFGEFSGPIDPILVFGGSNESIKGAEMYYTARTIMITVLIRGPEDQAIAWETAFLNMMSRYEMKHANFTFMTETSVAEEIHTAVETDKIVSVIACAAVLIWVITMLGINHWPESSILSALVHHKLLISISAVMISVISVWCSIGMFSLFGVHATDNAIVVLFFVITCLGINRIFVIIRTFQANGHCYGLPNISYREMNHRISNVMRRSIPIVLTNSLICSTCLFLAGGVLPYVSVSMPAVEVFARHAGLAILMDTAFYLLVMLPLFQYDARREMSGKCEIWPWYELSNESKINLCMEAVDGNLRSPVDWFKLAIAPLLLKKICRIWIATFFFVSLIIACYCTLCLEFGFNQVMAFSETSYLTKHFQNMNENLNIGPPLWFVVEGDVKWHDPKMQNKFCTLAGCDDNSMGNKIRSLAYAENYKGNYLHGDVNIWLDSYLQFMHPRGSCCKMDGKQFCDPSNATHCSSCSSSSVASLTTTEYEFYRNLHHFLETPPSIQCAHGGMALAKPAINLTRNGKIQSAYFSTFFKKLNLSDSIQLYDAWRFAKYLADDIERELEIPGVKVYVYSTFFPYYEQYLTLSTTVYTLVVLVLFVAFVTISLFLRVNLAGSLVTVFVLLSSYLHLMEWMYLLGITVNVVSVINMAMSLGIAVEFFGQMLHGFYNSKKPKREERAFAALVSNGSTTLSGIFPAIMITAGCLSFADSRVLITYFCNQLVGIGLVCAVHGVVYMPTLLAIFGSDFYQNVSSEEESTDEAELQDTPPSTTSSTSSTSETSV
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying entries 1 - 10 of 11 in total
Position Description PubMed ID GlyTouCan ID Source
48 N-linked (GlcNAc...) asparagine
419 N-linked (GlcNAc...) asparagine
426 N-linked (GlcNAc...) asparagine
518 N-linked (GlcNAc...) asparagine
566 N-linked (GlcNAc...) asparagine
690 N-linked (GlcNAc...) asparagine
787 N-linked (GlcNAc...) asparagine
959 N-linked (GlcNAc...) asparagine
1010 N-linked (GlcNAc...) asparagine
1030 N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 2 entries
Pathway Name Organism
Intestinal lipid absorption Caenorhabditis elegans
LDL clearance Caenorhabditis elegans
Disease
Displaying 1 entry
DO ID Disease Name Source
DOID:14504 Niemann-Pick disease
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025