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5-hydroxytryptamine receptor 2C
Summary
- UniProt ID
- P34968
- Gene Symbol
- Htr2c 5ht1c Htr1c
- Gene ID
- 15560
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
- Behavior Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Reference proteome Signal Transmembrane helix
Gene Ontology (GO)
| GO Term | Evidence Code | Reference |
|---|---|---|
| behavioral fear response | ||
| intracellular calcium ion homeostasis | ||
| intracellular calcium ion homeostasis | ||
| G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger | ||
| phospholipase C-activating G protein-coupled receptor signaling pathway |
GO Hierarchy
biological process
cellular process [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of signaling [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
signal transduction [inference]
regulation of cell communication [inference]
regulation of metabolic process [inference]
positive regulation of cellular process [inference]
| GO Term | Evidence Code | Reference |
|---|---|---|
| plasma membrane | ||
| plasma membrane | ||
| plasma membrane | ||
| plasma membrane | ||
| external side of plasma membrane |
GO Hierarchy
| GO Term | Evidence Code | Reference |
|---|---|---|
| Gq/11-coupled serotonin receptor activity | ||
| Gq/11-coupled serotonin receptor activity | ||
| Gq/11-coupled serotonin receptor activity | ||
| G protein-coupled serotonin receptor activity | ||
| G protein-coupled serotonin receptor activity |
Sequence
MVNLGTAVRSLLVHLIGLLVWQFDISISPVAAIVTDTFNSSDGGRLFQFPDGVQNWPALSIVVIIIMTIGGNILVIMAVSMEKKLHNATNYFLMSLAIADMLVGLLVMPLSLLAILYDYVWPLPRYLCPVWISLDVLFSTASIMHLCAISLDRYVAIRNPIEHSRFNSRTKAIMKIAIVWAISIGVSVPIPVIGLRDESKVFVNNTTCVLNDPNFVLIGSFVAFFIPLTIMVITYFLTIYVLRRQTLMLLRGHTEEELRNISLNFLKCCCKKGDEEENAPNPNPDQKPRRKKKEKRPRGTMQAINNEKKASKVLGIVFFVFLIMWCPFFITNILSVLCGKACNQKLMEKLLNVFVWIGYVCSGINPLVYTLFNKIYRRAFSKYLRCDYKPDKKPPVRQIPRVAATALSGRELNVNIYRHTNERVVRKANDTEPGIEMQVENLELPVNPSNVVSERISSV
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| G alpha (q) signalling events | Mus musculus |
| Serotonin receptors | Mus musculus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:11983 | Prader-Willi syndrome | |
| DOID:9352 | type 2 diabetes mellitus |
