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5-hydroxytryptamine receptor 2A

Summary

UniProt ID

P35363

Gene Symbol

Htr2
Htr2a

Gene ID

15558

Organism

Mus musculus (house mouse)

External Links

PubChem: P35363
Re-Glyco: P35363

Annotation

Keyword

Behavior
Cell membrane
Cell projection
Cytoplasmic vesicle
Disulfide bond
G-protein coupled receptor
Glycoprotein
Phosphoprotein
Reference proteome
Synapse
Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 10** of 11 in total

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GO Term
axon
cytoplasmic vesicle
neuronal cell body
postsynaptic membrane
neurofilament
caveola
presynaptic membrane
dendritic shaft
cell body fiber
G protein-coupled serotonin receptor complex

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying entries **1 - 10** of 33 in total

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GO Term
positive regulation of cytosolic calcium ion concentration
negative regulation of synaptic transmission, glutamatergic
presynaptic modulation of chemical synaptic transmission
positive regulation of execution phase of apoptosis
positive regulation of platelet aggregation
temperature homeostasis
positive regulation of cytokine production involved in immune response
glycolytic process
intracellular calcium ion homeostasis
memory

Displaying **all 8** entries
GO Term
serotonin receptor activity
identical protein binding
protein-containing complex binding
G protein-coupled serotonin receptor activity
serotonin binding
Gq/11-coupled serotonin receptor activity
protein tyrosine kinase activator activity
1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding

Annotation information from UniProt.

Sequence

MEILCEDNISLSSIPNSLMQLGDDSRLYPNDFNSRDANTSEASNWTIDAENRTNLSCEGYLPPTCLSILHLQEKNWSALLTTVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNPIHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVAFFIPLTIMVITYFLTIKSLQKEATLCVSDLSTRAKLSSFSFLPQSSLSSEKLFQRSIHREPGSYAGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNENVIGALLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENRKPLQLILVNTIPTLAYKSSQLQVGQKKNSQEDAEPTANDCSMVTLGNQHSEEMCTDNIETVNEKVSCV

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 5** entries
Position	Description	Source
8	N-linked (GlcNAc...) asparagine	UniProt
38	N-linked (GlcNAc...) asparagine	UniProt
44	N-linked (GlcNAc...) asparagine	UniProt
51	N-linked (GlcNAc...) asparagine	UniProt
54	N-linked (GlcNAc...) asparagine	UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 2** entries
Pathway Name	Organism
G alpha (q) signalling events	Mus musculus
Serotonin receptors	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

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External Links

Annotation

International Collaboration

Acknowledgements