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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Cystathionine beta-synthase
Summary
- UniProt ID
- P35520
- Gene Symbol
-
- CBS
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- P35520
- PubChem
- P35520
- The Human Metabolome Database
- HMDBP00779
- The O-GlcNAc Database
- P35520
Annotation
- Keyword
-
- 3D-structure
- Allosteric enzyme
- Alternative splicing
- CBS domain
- Cysteine biosynthesis
- Cytoplasm
- Disease variant
- Heme
- Isopeptide bond
- Lyase
- Nucleus
- Phosphoprotein
- Pyridoxal phosphate
- Reference proteome
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| DNA protection |
| hydrogen sulfide biosynthetic process |
| GO Term |
|---|
| protein homodimerization activity |
| cystathionine beta-synthase activity |
| cysteine synthase activity |
| carbon monoxide binding |
| L-cysteine desulfhydrase activity |
| S-adenosyl-L-methionine binding |
Sequence
MPSETPQAEVGPTGCPHRSGPHSAKGSLEKGSPEDKEAKEPLWIRPDAPSRCTWQLGRPASESPHHHTAPAKSPKILPDILKKIGDTPMVRINKIGKKFGLKCELLAKCEFFNAGGSVKDRISLRMIEDAERDGTLKPGDTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIVRTPTNARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHYDTTADEILQQCDGKLDMLVASVGTGGTITGIARKLKEKCPGCRIIGVDPEGSILAEPEELNQTEQTTYEVEGIGYDFIPTVLDRTVVDKWFKSNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVKAAQELQEGQRCVVILPDSVRNYMTKFLSDRWMLQKGFLKEEDLTEKKPWWWHLRVQELGLSAPLTVLPTITCGHTIEILREKGFDQAPVVDEAGVILGMVTLGNMLSSLLAGKVQPSDQVGKVIYKQFKQIRLTDTLGRLSHILEMDHFALVVHEQIQYHSTGKSSQRQMVFGVVTAIDLLNFVAAQERDQK
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 434 |
|
|||
|
|
G43417UB
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Cysteine formation from homocysteine | Homo sapiens |
| Metabolism of ingested SeMet, Sec, MeSec into H2Se | Homo sapiens |
