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High affinity nerve growth factor receptor

Summary

UniProt ID

P35739

Gene Symbol

Ntrk1
Trk
Trka

Organism

Rattus norvegicus (Norway rat)

External Links

PubChem: P35739

Annotation

Keyword

ATP-binding
Alternative splicing
Cell membrane
Developmental protein
Differentiation
Disulfide bond
Endosome
Glycoprotein
Immunoglobulin domain
Leucine-rich repeat
Neurogenesis
Phosphoprotein
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix
Tyrosine-protein kinase
Ubl conjugation

Gene Ontology (GO)

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GO Term
mechanoreceptor differentiation
positive regulation of programmed cell death
negative regulation of neuron apoptotic process
sympathetic nervous system development
detection of temperature stimulus involved in sensory perception of pain
detection of mechanical stimulus involved in sensory perception of pain
neuron apoptotic process
response to electrical stimulus
positive regulation of synapse assembly
positive regulation of synaptic transmission, glutamatergic

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GO Term
Golgi membrane
cytoplasm
plasma membrane
axon
protein-containing complex
dendrite
neuronal cell body
receptor complex
recycling endosome membrane
early endosome membrane

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GO Term
protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
kinase binding
identical protein binding
protein homodimerization activity
transmembrane receptor protein serine/threonine kinase activity
GPI-linked ephrin receptor activity
neurotrophin receptor activity
neurotrophin p75 receptor binding
ATP binding

Annotation information from UniProt.

Sequence

MLRGQRHGQLGWHRPAAGLGGLVTSLMLACACAASCRETCCPVGPSGLRCTRAGTLNTLRGLRGAGNLTELYVENQRDLQRLEFEDLQGLGELRSLTIVKSGLRFVAPDAFHFTPRLSHLNLSSNALESLSWKTVQGLSLQDLTLSGNPLHCSCALLWLQRWEQEDLCGVYTQKLQGSGSGDQFLPLGHNNSCGVPSVKIQMPNDSVEVGDDVFLQCQVEGQALQQADWILTELEGTATMKKSGDLPSLGLTLVNVTSDLNKKNVTCWAENDVGRAEVSVQVSVSFPASVHLGKAVEQHHWCIPFSVDGQPAPSLRWFFNGSVLNETSFIFTQFLESALTNETMRHGCLRLNQPTHVNNGNYTLLAANPYGQAAASIMAAFMDNPFEFNPEDPIPVSFSPVDTNSTSRDPVEKKDETPFGVSVAVGLAVSAALFLSALLLVLNKCGQRSKFGINRPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIMENPQYFSDTCVHHIKRQDIILKWELGEGAFGKVFLAECYNLLNDQDKMLVAVKALKETSENARQDFHREAELLTMLQHQHIVRFFGVCTEGGPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLASLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFSTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIECITQGRELERPRACPPDVYAIMRGCWQREPQQRLSMKDVHARLQALAQAPPSYLDVLG

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

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Position	Description	PubMed ID	GlyTouCan ID	Source
404	N-linked (GlcNAc...) asparagine			UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 5** entries
Pathway Name	Organism
ARMS-mediated activation	Rattus norvegicus
Frs2-mediated activation	Rattus norvegicus
PI3K/AKT activation	Rattus norvegicus
Retrograde neurotrophin signalling	Rattus norvegicus
TRKA activation by NGF	Rattus norvegicus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

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Summary

External Links

Annotation

International Collaboration

Acknowledgements