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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
High affinity nerve growth factor receptor
Summary
- UniProt ID
- P35739
- Gene Symbol
-
- Ntrk1
- Trk
- Trka
- Organism
- Rattus norvegicus (Norway rat)
External Links
- PubChem
- P35739
Annotation
- Keyword
-
- ATP-binding
- Alternative splicing
- Cell membrane
- Developmental protein
- Differentiation
- Disulfide bond
- Endosome
- Glycoprotein
- Immunoglobulin domain
- Leucine-rich repeat
- Neurogenesis
- Phosphoprotein
- Receptor
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Tyrosine-protein kinase
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| positive regulation of ERK1 and ERK2 cascade |
| cellular response to nicotine |
| GO Term |
|---|
| Golgi membrane |
| cytoplasm |
| plasma membrane |
| axon |
| protein-containing complex |
| dendrite |
| neuronal cell body |
| receptor complex |
| recycling endosome membrane |
| early endosome membrane |
| GO Term |
|---|
| nerve growth factor receptor activity |
| neurotrophin binding |
| nerve growth factor binding |
Sequence
MLRGQRHGQLGWHRPAAGLGGLVTSLMLACACAASCRETCCPVGPSGLRCTRAGTLNTLRGLRGAGNLTELYVENQRDLQRLEFEDLQGLGELRSLTIVKSGLRFVAPDAFHFTPRLSHLNLSSNALESLSWKTVQGLSLQDLTLSGNPLHCSCALLWLQRWEQEDLCGVYTQKLQGSGSGDQFLPLGHNNSCGVPSVKIQMPNDSVEVGDDVFLQCQVEGQALQQADWILTELEGTATMKKSGDLPSLGLTLVNVTSDLNKKNVTCWAENDVGRAEVSVQVSVSFPASVHLGKAVEQHHWCIPFSVDGQPAPSLRWFFNGSVLNETSFIFTQFLESALTNETMRHGCLRLNQPTHVNNGNYTLLAANPYGQAAASIMAAFMDNPFEFNPEDPIPVSFSPVDTNSTSRDPVEKKDETPFGVSVAVGLAVSAALFLSALLLVLNKCGQRSKFGINRPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIMENPQYFSDTCVHHIKRQDIILKWELGEGAFGKVFLAECYNLLNDQDKMLVAVKALKETSENARQDFHREAELLTMLQHQHIVRFFGVCTEGGPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLASLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFSTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIECITQGRELERPRACPPDVYAIMRGCWQREPQQRLSMKDVHARLQALAQAPPSYLDVLG
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 67 | N-linked (GlcNAc...) asparagine |
|
||
| 121 | N-linked (GlcNAc...) asparagine |
|
||
| 190 | N-linked (GlcNAc...) asparagine |
|
||
| 204 | N-linked (GlcNAc...) asparagine |
|
||
| 255 | N-linked (GlcNAc...) asparagine |
|
||
| 264 | N-linked (GlcNAc...) asparagine |
|
||
| 320 | N-linked (GlcNAc...) asparagine |
|
||
| 325 | N-linked (GlcNAc...) asparagine |
|
||
| 341 | N-linked (GlcNAc...) asparagine |
|
||
| 361 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| ARMS-mediated activation | Rattus norvegicus |
| Frs2-mediated activation | Rattus norvegicus |
| PI3K/AKT activation | Rattus norvegicus |
| Retrograde neurotrophin signalling | Rattus norvegicus |
| TRKA activation by NGF | Rattus norvegicus |
