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Fragile X messenger ribonucleoprotein 1

Summary

UniProt ID

P35922

Gene Symbol

Fmr1
Fmr-1

Organism

Mus musculus (house mouse)

External Links

GlyGen: P35922
The O-GlcNAc Database: P35922

Annotation

Keyword

Acetylation
Activator
Alternative splicing
Cell membrane
Cell projection
Centromere
Chromosome
Cytoplasm
DNA damage
Methylation
Neurogenesis
Nucleus
Phosphoprotein
Postsynaptic cell membrane
RNA-binding
RNA-mediated gene silencing
Reference proteome
Repeat
Repressor
Ribonucleoprotein
Synaptosome
Translation regulation
Ubl conjugation
mRNA splicing
mRNA transport

Gene Ontology (GO)

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GO Term
excitatory chemical synaptic transmission
negative regulation of protein processing
negative regulation of translation
negative regulation of neuron apoptotic process
negative regulation of neuron differentiation
positive regulation of translation
negative regulation of translational initiation
regulation of neuronal action potential
regulation of translation at presynapse, modulating synaptic transmission
regulation of translation at postsynapse, modulating synaptic transmission

Displaying entries **31 - 40** of 43 in total

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GO Term
chromocenter
cytoplasmic stress granule
postsynaptic density
filopodium tip
presynaptic membrane
dendritic spine
perinuclear region of cytoplasm
neuronal ribonucleoprotein granule
spine apparatus
Schaffer collateral - CA1 synapse

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GO Term
chromatin binding
RNA binding
microtubule binding
protein kinase binding
translation regulator activity
N6-methyladenosine-containing RNA reader activity
sequence-specific mRNA binding
protein domain specific binding
protein homodimerization activity
protein heterodimerization activity

Annotation information from UniProt.

Sequence

MEELVVEVRGSNGAFYKAFVKDVHEDSITVAFENNWQPERQIPFHDVRFPPPVGYNKDINESDEVEVYSRANEKEPCCWWLAKVRMIKGEFYVIEYAACDATYNEIVTIERLRSVNPNKPATKDTFHKIKLEVPEDLRQMCAKESAHKDFKKAVGAFSVTYDPENYQLVILSINEVTSKRAHMLIDMHFRSLRTKLSLILRNEEASKQLESSRQLASRFHEQFIVREDLMGLAIGTHGANIQQARKVPGVTAIDLDEDTCTFHIYGEDQDAVKKARSFLEFAEDVIQVPRNLVGKVIGKNGKLIQEIVDKSGVVRVRIEAENEKSVPQEEEIMPPSSLPSNNSRVGPNSSEEKKHLDTKENTHFSQPNSTKVQRVLVVSSIVAGGPQKPEPKAWQGMVPFVFVGTKDSIANATVLLDYHLNYLKEVDQLRLERLQIDEQLRQIGASSRPPPNRTDKEKGYVTDDGQGMGRGSRPYRNRGHGRRGPGYTSGTNSEASNASETESDHRDELSDWSLAPTEEERESFLRRGDGRRRRGGGRGQGGRGRGGGFKGNDDHSRTDNRPRNPREAKGRTADGSLQSASSEGSRLRTGKDRNQKKEKPDSVDGLQPLVNGVP

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites