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Low-density lipoprotein receptor

Summary

UniProt ID

P35951

Gene Symbol

Ldlr

Gene ID

16835

Organism

Mus musculus (house mouse)

External Links

GlycoProtDB: GPDB0003602
GlyGen: P35951
PubChem: P35951
Re-Glyco: P35951

Annotation

Keyword

Cell membrane
Cholesterol metabolism
Coated pit
Disulfide bond
EGF-like domain
Endocytosis
Endosome
Glycoprotein
Golgi apparatus
LDL
Lipid transport
Lysosome
Phosphoprotein
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix
Ubl conjugation

Gene Ontology (GO)

Displaying entries **1 - 10** of 17 in total

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GO Term
external side of plasma membrane
cell surface
basolateral plasma membrane
apical part of cell
clathrin-coated pit
low-density lipoprotein particle
sorting endosome
PCSK9-LDLR complex
extracellular space
lysosome

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying entries **1 - 10** of 37 in total

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GO Term
long-term memory
positive regulation of triglyceride biosynthetic process
regulation of phosphatidylcholine catabolic process
plasma lipoprotein particle clearance
negative regulation of astrocyte activation
cholesterol import
regulation of cholesterol metabolic process
negative regulation of microglial cell activation
receptor-mediated endocytosis
cholesterol metabolic process

Displaying **all 7** entries
GO Term
calcium ion binding
low-density lipoprotein particle receptor activity
low-density lipoprotein particle binding
very-low-density lipoprotein particle receptor activity
amyloid-beta binding
protease binding
identical protein binding

Annotation information from UniProt.

Sequence

MSTADLMRRWVIALLLAAAGVAAEDSCSRNEFQCRDGKCIASKWVCDGSPECPDGSDESPETCMSVTCQSNQFSCGGRVSRCIPDSWRCDGQVDCENDSDEQGCPPKTCSQDDFRCQDGKCISPQFVCDGDRDCLDGSDEAHCQATTCGPAHFRCNSSICIPSLWACDGDVDCVDGSDEWPQNCQGRDTASKGVSSPCSSLEFHCGSSECIHRSWVCDGEADCKDKSDEEHCAVATCRPDEFQCADGSCIHGSRQCDREHDCKDMSDELGCVNVTQCDGPNKFKCHSGECISLDKVCDSARDCQDWSDEPIKECKTNECLDNNGGCSHICKDLKIGSECLCPSGFRLVDLHRCEDIDECQEPDTCSQLCVNLEGSYKCECQAGFHMDPHTRVCKAVGSIGYLLFTNRHEVRKMTLDRSEYTSLLPNLKNVVALDTEVTNNRIYWSDLSQKKIYSALMDQAPNLSYDTIISEDLHAPDGLAVDWIHRNIYWTDSVPGSVSVADTKGVKRRTLFQEAGSRPRAIVVDPVHGFMYWTDWGTPAKIKKGGLNGVDIHSLVTENIQWPNGITLDLSSGRLYWVDSKLHSISSIDVNGGNRKTILEDENRLAHPFSLAIYEDKVYWTDVINEAIFSANRLTGSDVNLVAENLLSPEDIVLFHKVTQPRGVNWCETTALLPNGGCQYLCLPAPQIGPHSPKFTCACPDGMLLAKDMRSCLTEVDTVLTTQGTSAVRPVVTASATRPPKHSEDLSAPSTPRQPVDTPGLSTVASVTVSHQVQGDMAGRGNEEQPHGMRFLSIFFPIALVALLVLGAVLLWRNWRLKNINSINFDNPVYQKTTEDELHICRSQDGYTYPSRQMVSLEDDVA

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 3** entries
Position	Description	GlyTouCan ID	Source
97	N-linked (GlcNAc...) asparagine		UniProt GlyGen
273	N-linked (GlcNAc...) asparagine	G41247ZX	GlycoProtDB UniProt GlyGen
462	N-linked (GlcNAc...) asparagine		UniProt GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 4** entries
Pathway Name	Organism
Cargo recognition for clathrin-mediated endocytosis	Mus musculus
Chylomicron clearance	Mus musculus
Clathrin-mediated endocytosis	Mus musculus
LDL clearance	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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Summary

External Links

Annotation

International Collaboration

Acknowledgements