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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial
Summary
- UniProt ID
- P36957
- Gene Symbol
-
- DLST
- DLTS
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Acyltransferase
- Alternative splicing
- Direct protein sequencing
- Disease variant
- Lipoyl
- Mitochondrion
- Nucleus
- Phosphoprotein
- Reference proteome
- Transit peptide
- Tricarboxylic acid cycle
- Gene Ontology (GO)
| GO Term |
|---|
| nucleus |
| membrane |
| mitochondrion |
| mitochondrial matrix |
| cytosol |
| nucleoplasm |
| oxoglutarate dehydrogenase complex |
| GO Term |
|---|
| acyltransferase activity |
| dihydrolipoyllysine-residue succinyltransferase activity |
Sequence
MLSRSRCVSRAFSRSLSAFQKGNCPLGRRSLPGVSLCQGPGYPNSRKVVINNSVFSVRFFRTTAVCKDDLVTVKTPAFAESVTEGDVRWEKAVGDTVAEDEVVCEIETDKTSVQVPSPANGVIEALLVPDGGKVEGGTPLFTLRKTGAAPAKAKPAEAPAAAAPKAEPTAAAVPPPAAPIPTQMPPVPSPSQPPSGKPVSAVKPTVAPPLAEPGAGKGLRSEHREKMNRMRQRIAQRLKEAQNTCAMLTTFNEIDMSNIQEMRARHKEAFLKKHNLKLGFMSAFVKASAFALQEQPVVNAVIDDTTKEVVYRDYIDISVAVATPRGLVVPVIRNVEAMNFADIERTITELGEKARKNELAIEDMDGGTFTISNGGVFGSLFGTPIINPPQSAILGMHGIFDRPVAIGGKVEVRPMMYVALTYDHRLIDGREAVTFLRKIKAAVEDPRVLLLDL
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 3 |
|
|||
| 5 |
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Glycine degradation | Homo sapiens |
| Lysine catabolism | Homo sapiens |
| Protein lipoylation | Homo sapiens |
| Succinyl-CoA Biosynthesis | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:10286 | prostate carcinoma | |
| DOID:10652 | Alzheimer's disease | |
| DOID:10914 | amnestic disorder | |
| DOID:10915 | Wernicke-Korsakoff syndrome | |
| DOID:10952 | nephritis | |
| DOID:11561 | hypertensive retinopathy | |
| DOID:117 | heart cancer | |
| DOID:11870 | Pick's disease | |
| DOID:12236 | primary biliary cholangitis | |
| DOID:12271 | aniridia |
