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TGF-beta receptor type-2

Summary

UniProt ID

P38438

Gene Symbol

Tgfbr2

Organism

Rattus norvegicus (Norway rat)

External Links

PubChem: P38438

Annotation

Keyword

ATP-binding
Apoptosis
Cell membrane
Differentiation
Disulfide bond
Glycoprotein
Growth regulation
Magnesium
Manganese
Metal-binding
Phosphoprotein
Receptor
Reference proteome
Serine/threonine-protein kinase
Signal
Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 10** of 80 in total

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GO Term
smoothened signaling pathway
heart development
response to nutrient
response to xenobiotic stimulus
positive regulation of epithelial cell migration
positive regulation of epithelial to mesenchymal transition
animal organ regeneration
response to estrogen
digestive tract development
embryonic cranial skeleton morphogenesis

Displaying **all 8** entries
GO Term
external side of plasma membrane
cell surface
plasma membrane
membrane
receptor complex
caveola
membrane raft
transforming growth factor beta ligand-receptor complex

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GO Term
activin receptor activity
type I transforming growth factor beta receptor binding
protein homodimerization activity
protein-containing complex binding
SMAD binding
activin binding
transforming growth factor beta binding
molecular adaptor activity
kinase activator activity
mitogen-activated protein kinase kinase kinase binding

Annotation information from UniProt.

Sequence

MGRGLLRGLWPLHIVLWTRIASTIPPHVPKSVNSDLMAGDNSGAVKLPQLCKFCDVTLSTCDNQKSCMSNCSVTSICEKPQEVCVAVWRKNDKNITLETVCHDPKFTYHGFTLEDATSPTCVMKEKKRAGETFFMCSCNTEECNDYIIFNEEYTTSSPDLLLVIIQVTGVSLLPPLGIAIAVIAIFYCYRVHRQQKLSPSWESSKPRKLMDFSDNCAIILEDDRSDISSTCANNINHNTELLPIELDTLVGKGRFAEVYKAKLKQNTSEQFETVAVKIFPYEEYSSWKTEKDIFSDINLKHENILQFLTAEERKTEMGKQYWLITAFHAKGNLQEYLTRHVISWEDLRKLGSSLARGIAHLHSDHTPCGRPKMPIVHRDLKSSNILVKNDLTCCLCDFGLSLRLDPTLSVDDLANSGQVGTARYMAPEVLESRMNLENMESFKQTDVYSMALVLWEMTSRCNAVGEVKDYEPPFGSKVREHPCVESMKDNVLRDRGRPEIPSFWLNHQGIQIVCETLTECWDHDPEARLTAQCVAERFSELEHPDRLSGRSCSQEKIPEDGSLNTTK

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
70	N-linked (GlcNAc...) asparagine			UniProt
94	N-linked (GlcNAc...) asparagine			UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 4** entries
Pathway Name	Organism
Downregulation of TGF-beta receptor signaling	Rattus norvegicus
TGF-beta receptor signaling activates SMADs	Rattus norvegicus
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)	Rattus norvegicus
TGFBR3 regulates TGF-beta signaling	Rattus norvegicus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

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Summary

External Links

Annotation

International Collaboration

Acknowledgements