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Heat shock factor protein 1

Summary

UniProt ID

P38532

Gene Symbol

Hsf1

Gene ID

15499

Organism

Mus musculus (house mouse)

External Links

GlyGen: P38532
PubChem: P38532
O-GlcNAcAtlas: P38532
Re-Glyco: P38532

Annotation

Keyword

Acetylation
Activator
Alternative splicing
Centromere
Chromosome
Cytoskeleton
DNA repair
DNA-binding
Isopeptide bond
Kinetochore
Nucleus
Phosphoprotein
Reference proteome
Stress response
Transcription regulation
Ubl conjugation
mRNA processing
mRNA transport

Gene Ontology (GO)

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GO Term
nucleus
cytoplasm
pronucleus
nuclear stress granule
mitotic spindle pole
protein-containing complex
nucleoplasm
cytosol
perinuclear region of cytoplasm
kinetochore

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

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GO Term
embryonic process involved in female pregnancy
in utero embryonic development
mRNA processing
response to heat
negative regulation of protein-containing complex assembly
response to lipopolysaccharide
negative regulation of tumor necrosis factor production
cellular response to heat
positive regulation of multicellular organism growth
protein-containing complex assembly

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GO Term
chromatin DNA binding
identical protein binding
sequence-specific DNA binding
protein heterodimerization activity
heat shock protein binding
Hsp90 protein binding
chromatin binding
RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding
translation elongation factor binding
RNA polymerase II cis-regulatory region sequence-specific DNA binding

Annotation information from UniProt.

Sequence

MDLAVGPGAAGPSNVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLPKYFKHNNMASFVRQLNMYGFRKVVHIEQGGLVKPERDDTEFQHPCFLRGQEQLLENIKRKVTSVSTLKSEDIKIRQDSVTRLLTDVQLMKGKQECMDSKLLAMKHENEALWREVASLRQKHAQQQKVVNKLIQFLISLVQSNRILGVKRKIPLMLSDSNSAHSVPKYGRQYSLEHVHGPGPYSAPSPAYSSSSLYSSDAVTSSGPIISDITELAPTSPLASPGRSIDERPLSSSTLVRVKQEPPSPPHSPRVLEASPGRPSSMDTPLSPTAFIDSILRESEPTPAASNTAPMDTTGAQAPALPTPSTPEKCLSVACLDKNELSDHLDAMDSNLDNLQTMLTSHGFSVDTSALLDLFSPSVTMPDMSLPDLDSSLASIQELLSPQEPPRPIEAENSNPDSGKQLVHYTAQPLFLLDPDAVDTGSSELPVLFELGESSYFSEGDDYTDDPTISLLTGTEPHKAKDPTVS

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 4** entries
Position	GlyTouCan ID	Source
292	G49108TO	GlyGen
293	G49108TO	GlyGen
341		GlyGen
362		GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 5** entries
Pathway Name	Organism
Attenuation phase	Mus musculus
HSF1 activation	Mus musculus
HSF1-dependent transactivation	Mus musculus
Mitochondrial unfolded protein response (UPRmt)	Mus musculus
Regulation of HSF1-mediated heat shock response	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

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Guidelines

Summary

External Links

Annotation

International Collaboration

Acknowledgements