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Dynamin-2
Summary
- UniProt ID
- P39054
- Gene Symbol
-
- Dnm2
- Dyn2
- Gene ID
- 13430
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Acetylation
- Alternative splicing
- Cell junction
- Cell projection
- Coated pit
- Cytoplasmic vesicle
- Cytoskeleton
- Direct protein sequencing
- Endocytosis
- Endosome
- GTP-binding
- Hydrolase
- Microtubule
- Motor protein
- Phagocytosis
- Phosphoprotein
- Reference proteome
- Synaptosome
- Gene Ontology (GO)
| GO Term |
|---|
| phagocytic vesicle membrane |
| cell junction |
| neuron projection |
| anchoring junction |
| presynapse |
| endosome |
| clathrin-coated vesicle |
| photoreceptor inner segment |
| podosome |
| centrosome |
| GO Term |
|---|
| actin filament bundle organization |
| membrane tubulation |
| vesicle scission |
| receptor-mediated endocytosis |
| autophagy |
| phagocytosis |
| centrosome cycle |
| synaptic vesicle endocytosis |
| coronary vasculature development |
| ventricular septum development |
| GO Term |
|---|
| GTP binding |
| membrane scission GTPase motor activity |
| GTPase activity |
| phosphatidylinositol-4,5-bisphosphate binding |
Sequence
MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLILQLIFSKTEYAEFLHCKSKKFTDFDEVRQEIEAETDRVTGTNKGISPVPINLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANMDLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQKDIEGKKDIRAALAAERKFFLSHPAYRHMADRMGTPHLQKTLNQQLTNHIRESLPTLRSKLQSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGARINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDLAFEAIVKKQVVKLKEPCLKCVDLVIQELISTVRQCTSKLSSYPRLREETERIVTTYIREREGRTKDQILLLIDIEQSYINTNHEDFIGFANAQQRSTQLNKKRAIPNQGEILVIRRGWLTINNISLMKGGSKEYWFVLTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDLRQIELACDSQEDVDSWKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLVDSYVAIINKSIRDLMPKTIMHLMINNTKAFIHHELLAYLYSSADQSSLMEESAEQAQRRDDMLRMYHALKEALNIIGDISTSTVSTPVPPPVDDTWLQNTSGHSPTPQRRPVSSVHPPGRPPAVRGPTPGPPLIPMPVGATSSFSAPPIPSRPGPQSVFANNDPFSAPPQIPSRPARIPPGIPPGVPSRRAPAAPSRPTIIRPAEPSLLD
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Clathrin-mediated endocytosis | Mus musculus |
| Formation of annular gap junctions | Mus musculus |
| Gap junction degradation | Mus musculus |
| Golgi Associated Vesicle Biogenesis | Mus musculus |
| Lysosome Vesicle Biogenesis | Mus musculus |
| MHC class II antigen presentation | Mus musculus |
| NOSTRIN mediated eNOS trafficking | Mus musculus |
| Recycling pathway of L1 | Mus musculus |
| Toll Like Receptor 4 (TLR4) Cascade | Mus musculus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:11252 | microcytic anemia | |
| DOID:14717 | centronuclear myopathy | |
| DOID:2975 | cystic kidney disease | |
| DOID:423 | myopathy |
