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MIRAGE
Eukaryotic initiation factor 4F subunit p150
Summary
- UniProt ID
- P39935
- Gene Symbol
-
- TIF4631
- YGR162W
- Gene ID
- 853071
- Organism
- Saccharomyces cerevisiae S288C
Annotation
- Keyword
-
- 3D-structure
- Cytoplasm
- Initiation factor
- Phosphoprotein
- RNA-binding
- Reference proteome
- Translation regulation
- Gene Ontology (GO)
| GO Term |
|---|
| cytoplasm |
| mitochondrion |
| ribosome |
| P-body |
| cytoplasmic stress granule |
| eukaryotic translation initiation factor 4F complex |
| GO Term |
|---|
| molecular condensate scaffold activity |
| ATPase activator activity |
| RNA binding |
| mRNA binding |
| translation initiation factor activity |
Sequence
MTDETAHPTQSASKQESAALKQTGDDQQESQQQRGYTNYNNGSNYTQKKPYNSNRPHQQRGGKFGPNRYNNRGNYNGGGSFRGGHMGANSSNVPWTGYYNNYPVYYQPQQMAAAGSAPANPIPVEEKSPVPTKIEITTKSGEHLDLKEQHKAKLQSQERSTVSPQPESKLKETSDSTSTSTPTPTPSTNDSKASSEENISEAEKTRRNFIEQVKLRKAALEKKRKEQLEGSSGNNNIPMKTTPENVEEKGSDKPEVTEKTKPAEEKSAEPEVKQETPAEEGEQGEKGQIKEESTPKVLTFAERLKLKKQQKEREEKTEGKENKEVPVQEETKSAIESAPVPPSEQVKEETEVAETEQSNIDESATTPAIPTKSDEAEAEVEAEAGDAGTKIGLEAEIETTTDETDDGTNTVSHILNVLKDATPIEDVFSFNYPEGIEGPDIKYKKEHVKYTYGPTFLLQFKDKLNVKADAEWVQSTASKIVIPPGMGRGNRSRDSGRFGNNSSRGHDFRNTSVRNMDDRANSRTSSKRRSKRMNDDRRSNRSYTSRRDRERGSYRNEEKREDDKPKEEVAPLVPSANRWVPKFKSKKTEKKLAPDGKTELLDKDEVERKMKSLLNKLTLEMFDAISSEILAIANISVWETNGETLKAVIEQIFLKACDEPHWSSMYAQLCGKVVKELNPDITDETNEGKTGPKLVLHYLVARCHAEFDKGWTDKLPTNEDGTPLEPEMMSEEYYAAASAKRRGLGLVRFIGFLYRLNLLTGKMMFECFRRLMKDLTDSPSEETLESVVELLNTVGEQFETDSFRTGQATLEGSQLLDSLFGILDNIIQTAKISSRIKFKLIDIKELRHDKNWNSDKKDNGPKTIQQIHEEEERQRQLKNNSRSNSRRTNNSSNRHSFRRDAPPASKDSFITTRTYSQRNSQRAPPPKEEPAAPTSTATNMFSALMGESDDEE
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 185 |
|
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S | Saccharomyces cerevisiae |
| Deadenylation of mRNA | Saccharomyces cerevisiae |
| L13a-mediated translational silencing of Ceruloplasmin expression | Saccharomyces cerevisiae |
| Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) | Saccharomyces cerevisiae |
| Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) | Saccharomyces cerevisiae |
| Ribosomal scanning and start codon recognition | Saccharomyces cerevisiae |
| Translation initiation complex formation | Saccharomyces cerevisiae |
| mTORC1-mediated signalling | Saccharomyces cerevisiae |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:14330 | Parkinson's disease |
