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Interleukin-6 receptor subunit beta

Summary

UniProt ID

P40190

Gene Symbol

Il6st

Organism

Rattus norvegicus (Norway rat)

External Links

PubChem: P40190

Annotation

Keyword

Cell membrane
Disulfide bond
Glycoprotein
Immunoglobulin domain
Phosphoprotein
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix

Gene Ontology (GO)

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GO Term
glycogen metabolic process
signal transduction
positive regulation of cell population proliferation
cytokine-mediated signaling pathway
positive regulation of smooth muscle cell migration
response to cytokine
positive regulation of T cell proliferation
negative regulation of neuron apoptotic process
positive regulation of osteoblast differentiation
positive regulation of astrocyte differentiation

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GO Term
plasma membrane
dendrite
neuronal cell body
receptor complex
cell body
membrane raft
interleukin-6 receptor complex
oncostatin-M receptor complex
external side of plasma membrane
neuronal cell body membrane

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GO Term
cytokine receptor activity
cytokine binding
protein tyrosine kinase activator activity
identical protein binding
ciliary neurotrophic factor receptor activity
interleukin-6 receptor activity
interleukin-6 binding
ciliary neurotrophic factor receptor binding
coreceptor activity
growth factor binding

Annotation information from UniProt.

Sequence

MSALRIWLMQALLIFLTTESIGQLVEPCGYIYPEFPVVQRGSNFTATCVLKEKCLQVYSVNATYIVWKTNHVAVPKEQVTVINRTASSVTFTDVVFQNVQLTCNILSFGQIEQNVYGITILSGYPPDIPTNLSCIVNEGKNMLCQLDPGRETYLETNYTLKSEWATEKFPDCRTKHGTSSCMMGYTPIYFVNIEVWVEAENALGNVSSEPINFDPVDKVKPSPPHNLSVTNSEELSSILKLAWVNSGLDSILRLKSDIQYRTKDASTWIQVPLEDTVSPRTSFTVQDLKPFTEYVFRIRSIKENGKGYWSDWSEEASGTTYEDRPSKAPSFWYKVNANHPQEYRSARLIWKTLPLSEANGKILDYEVVLTQSKSVSQTYTVNGTELIVNLTNNRYVASLAARNVVGKSPATVLTIPGSHFKASHPVVDLKAFPKDNLLWVEWTPPSKPVNKYILEWCVLSENSPCIPDWQQEDGTVNRTHLRGSLLESKCYLITVTPVFPGGPGSPESMKAYLKQAAPSKGPTVRTKKVGKNEAVLEWDHLPVDVQNGFIRNYSISYRTSVGKEMVVRVDSSHTEYTLSSLSSDTLYMVHMAAYTEEGGKDGPEFTFTTLKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPPRHNFNSKDQMYSDANFTDVSVVEIEANNKKPCPDDLKSLDLFKKEKISTEGHSSGIGGSSCMSSSRPSISSSEENESAQSTASTVQYSTVVHSGYRHQVPSVQVFSRSESTQPLLDSEERPEDLQLVDSVDSGDEILPRQQYFKQSCSQPGASPDVSHFGRSSQVPSGSEEDFVRLKQQQVSDHISEPYGSEQRRLFQEGSVADALGTGTDGQIERFESVGMETAMDEDISKSYLPQTVRQGGYMPQ

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

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Position	Description	Source
43	N-linked (GlcNAc...) asparagine	UniProt
61	N-linked (GlcNAc...) asparagine	UniProt
83	N-linked (GlcNAc...) asparagine	UniProt
131	N-linked (GlcNAc...) asparagine	UniProt
157	N-linked (GlcNAc...) asparagine	UniProt
205	N-linked (GlcNAc...) asparagine	UniProt
226	N-linked (GlcNAc...) asparagine	UniProt
382	N-linked (GlcNAc...) asparagine	UniProt
389	N-linked (GlcNAc...) asparagine	UniProt
477	N-linked (GlcNAc...) asparagine	UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 6** entries
Pathway Name	Organism
IL-6-type cytokine receptor ligand interactions	Rattus norvegicus
Interleukin-27 signaling	Rattus norvegicus
Interleukin-35 Signalling	Rattus norvegicus
Interleukin-6 signaling	Rattus norvegicus
MAPK1 (ERK2) activation	Rattus norvegicus
MAPK3 (ERK1) activation	Rattus norvegicus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

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Summary

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Annotation

International Collaboration

Acknowledgements