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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Nicotinamide phosphoribosyltransferase
Summary
- UniProt ID
- P43490
- Gene Symbol
-
- NAMPT
- PBEF
- PBEF1
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- P43490
- PubChem
- P43490
- The Human Metabolome Database
- HMDBP08864
- The O-GlcNAc Database
- P43490
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Biological rhythms
- Cytokine
- Cytoplasm
- Glycosyltransferase
- Nucleus
- Phosphoprotein
- Pyridine nucleotide biosynthesis
- Reference proteome
- Secreted
- Gene Ontology (GO)
| GO Term |
|---|
| nuclear speck |
| cytosol |
| cell junction |
| extracellular exosome |
| GO Term |
|---|
| identical protein binding |
| nicotinamide phosphoribosyltransferase activity |
| cytokine activity |
Sequence
MNPAAEAEFNILLATDSYKVTHYKQYPPNTSKVYSYFECREKKTENSKLRKVKYEETVFYGLQYILNKYLKGKVVTKEKIQEAKDVYKEHFQDDVFNEKGWNYILEKYDGHLPIEIKAVPEGFVIPRGNVLFTVENTDPECYWLTNWIETILVQSWYPITVATNSREQKKILAKYLLETSGNLDGLEYKLHDFGYRGVSSQETAGIGASAHLVNFKGTDTVAGLALIKKYYGTKDPVPGYSVPAAEHSTITAWGKDHEKDAFEHIVTQFSSVPVSVVSDSYDIYNACEKIWGEDLRHLIVSRSTQAPLIIRPDSGNPLDTVLKVLEILGKKFPVTENSKGYKLLPPYLRVIQGDGVDINTLQEIVEGMKQKMWSIENIAFGSGGGLLQKLTRDLLNCSFKCSYVVTNGLGINVFKDPVADPNKRSKKGRLSLHRTPAGNFVTLEEGKGDLEEYGQDLLHTVFKNGKVTKSYSFDEIRKNAQLNIELEAAHH
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
|
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| BMAL1:CLOCK,NPAS2 activates circadian gene expression | Homo sapiens |
| NPAS4 regulates expression of target genes | Homo sapiens |
| Nicotinamide salvaging | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:9256 | colorectal cancer | |
| DOID:9351 | diabetes mellitus | |
| DOID:9352 | type 2 diabetes mellitus | |
| DOID:9408 | acute myocardial infarction | |
| DOID:9452 | steatotic liver disease | |
| DOID:9538 | multiple myeloma | |
| DOID:9744 | type 1 diabetes mellitus | |
| DOID:9952 | acute lymphoblastic leukemia | |
| DOID:9970 | obesity |
