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Transcriptional coactivator YAP1
Summary
- UniProt ID
- P46938
- Gene Symbol
-
- Yap
- Yap1
- Yap65
- Gene ID
- 22601
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- 3D-structure
- Activator
- Alternative splicing
- Cell junction
- Coiled coil
- Cytoplasm
- Nucleus
- Phosphoprotein
- Proto-oncogene
- Reference proteome
- Repeat
- Repressor
- Transcription regulation
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| cytoplasm |
| plasma membrane |
| cell-cell junction |
| membrane |
| nucleoplasm |
| cytosol |
| transcription regulator complex |
| bicellular tight junction |
| TEAD-YAP complex |
| nucleus |
Sequence
MEPAQQPPPQPAPQGPAPPSVSPAGTPAAPPAPPAGHQVVHVRGDSETDLEALFNAVMNPKTANVPQTVPMRLRKLPDSFFKPPEPKSHSRQASTDAGTAGALTPQHVRAHSSPASLQLGAVSPGTLTASGVVSGPAAAPAAQHLRQSSFEIPDDVPLPAGWEMAKTSSGQRYFLNHNDQTTTWQDPRKAMLSQLNVPAPASPAVPQTLMNSASGPLPDGWEQAMTQDGEVYYINHKNKTTSWLDPRLDPRFAMNQRITQSAPVKQPPPLAPQSPQGGVLGGGSSNQQQQIQLQQLQMEKERLRLKQQELFRQAIRNINPSTANAPKCQELALRSQLPTLEQDGGTPNAVSSPGMSQELRTMTTNSSDPFLNSGTYHSRDESTDSGLSMSSYSIPRTPDDFLNSVDEMDTGDTISQSTLPSQQSRFPDYLEALPGTNVDLGTLEGDAMNIEGEELMPSLQEALSSEILDVESVLAATKLDKESFLTWL
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 26 |
|
|
||
| 361 |
|
|||
| 364 |
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Nuclear signaling by ERBB4 | Mus musculus |
| RUNX1 regulates transcription of genes involved in differentiation of HSCs | Mus musculus |
| RUNX3 regulates YAP1-mediated transcription | Mus musculus |
| Signaling by Hippo | Mus musculus |
| Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells | Mus musculus |
| YAP1- and WWTR1 (TAZ)-stimulated gene expression | Mus musculus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050795 | cone dystrophy |
