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Transcriptional coactivator YAP1

Summary

UniProt ID

P46938

Gene Symbol

Yap1
Yap
Yap65

Organism

Mus musculus (house mouse)

External Links

GlyGen: P46938
PubChem: P46938
The O-GlcNAc Database: P46938
O-GlcNAcAtlas: P46938

Annotation

Keyword

3D-structure
Activator
Alternative splicing
Cell junction
Coiled coil
Cytoplasm
Nucleus
Phosphoprotein
Proto-oncogene
Reference proteome
Repeat
Repressor
Transcription regulation
Ubl conjugation

Gene Ontology (GO)

Displaying entries **1 - 10** of 60 in total

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GO Term
positive regulation of cell growth
negative regulation of transcription by RNA polymerase II
positive regulation of Notch signaling pathway
positive regulation of DNA-templated transcription
positive regulation of transcription by RNA polymerase II
positive regulation of canonical Wnt signaling pathway
tissue homeostasis
heart process
cell population proliferation
positive regulation of cell population proliferation

Displaying **all 9** entries
GO Term
nucleoplasm
cytosol
nucleus
cytoplasm
cell-cell junction
membrane
transcription regulator complex
TEAD-YAP complex
female germ cell nucleus

Displaying **all 7** entries
GO Term
transcription cis-regulatory region binding
RNA polymerase II cis-regulatory region sequence-specific DNA binding
transcription corepressor activity
DNA-binding transcription factor binding
proline-rich region binding
chromatin binding
transcription coactivator activity

Annotation information from UniProt.

Sequence

MEPAQQPPPQPAPQGPAPPSVSPAGTPAAPPAPPAGHQVVHVRGDSETDLEALFNAVMNPKTANVPQTVPMRLRKLPDSFFKPPEPKSHSRQASTDAGTAGALTPQHVRAHSSPASLQLGAVSPGTLTASGVVSGPAAAPAAQHLRQSSFEIPDDVPLPAGWEMAKTSSGQRYFLNHNDQTTTWQDPRKAMLSQLNVPAPASPAVPQTLMNSASGPLPDGWEQAMTQDGEVYYINHKNKTTSWLDPRLDPRFAMNQRITQSAPVKQPPPLAPQSPQGGVLGGGSSNQQQQIQLQQLQMEKERLRLKQQELFRQAIRNINPSTANAPKCQELALRSQLPTLEQDGGTPNAVSSPGMSQELRTMTTNSSDPFLNSGTYHSRDESTDSGLSMSSYSIPRTPDDFLNSVDEMDTGDTISQSTLPSQQSRFPDYLEALPGTNVDLGTLEGDAMNIEGEELMPSLQEALSSEILDVESVLAATKLDKESFLTWL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 3** entries
Position	GlyTouCan ID	Source
26		GlyGen
361	G49108TO	The O-GlcNAc Database
364	G49108TO	GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 6** entries
Pathway Name	Organism
Nuclear signaling by ERBB4	Mus musculus
RUNX1 regulates transcription of genes involved in differentiation of HSCs	Mus musculus
RUNX3 regulates YAP1-mediated transcription	Mus musculus
Signaling by Hippo	Mus musculus
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells	Mus musculus
YAP1- and WWTR1 (TAZ)-stimulated gene expression	Mus musculus