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RAC-beta serine/threonine-protein kinase

Summary

UniProt ID

P47197

Gene Symbol

Akt2

Organism

Rattus norvegicus (Norway rat)

External Links

GlyGen: P47197
PubChem: P47197
The O-GlcNAc Database: P47197

Annotation

Keyword

ATP-binding
Acetylation
Apoptosis
Cell membrane
Cytoplasm
Developmental protein
Disulfide bond
Endosome
Glucose metabolism
Glycogen biosynthesis
Glycogen metabolism
Glycoprotein
Manganese
Metal-binding
Nucleus
Phosphoprotein
Reference proteome
Serine/threonine-protein kinase
Sugar transport
Translation regulation
Ubl conjugation

Gene Ontology (GO)

Displaying entries **1 - 10** of 38 in total

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GO Term
positive regulation of protein phosphorylation
glycogen biosynthetic process
glucose metabolic process
regulation of translation
insulin receptor signaling pathway
positive regulation of signal transduction
positive regulation of gene expression
phosphorylation
positive regulation of cell migration
cellular response to insulin stimulus

Displaying **all 10** entries
GO Term
nucleus
plasma membrane
cell cortex
vesicle
cytosol
nucleoplasm
early endosome
sarcoplasmic reticulum
ruffle membrane
insulin-responsive compartment

Displaying **all 7** entries
GO Term
protein kinase activity
protein serine/threonine kinase activity
metal ion binding
molecular function activator activity
protein kinase C binding
ATP binding
protein serine kinase activity

Annotation information from UniProt.

Sequence

MNEVSVIKEGWLHKRGEYIKTWRPRYFLLKSDGSFIGYKERPEAPDQTLPPLNNFSVAECQLMKTERPRPNTFVIRCLQWTTVIERTFHVDSPDEREEWIRAIQMVANSLKQRGPGEDAMDYKCGSPSDSSTSEMMEVAVSKARAKVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGGDLFFHLSRERVFTEDRARFYGAEIVSALEYLHSTDVVYRDIKLENLMLDKDGHIKITDFGLSKEGISDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFPRTLGPEAKSLLAGLLKKDPKQRLGGGPSDAKEVMEHRFFLSINWQDVVQKKLLPPFKPQVTSEVDTRYFDDEFTAQSITITPPDRYDSLGSLELDQRTHFPQFSYSASIRE

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 5** entries
Position	Description	GlyTouCan ID	Source
128	O-linked (GlcNAc) serine		UniProt GlyGen
131	O-linked (GlcNAc) serine		UniProt GlyGen
306	O-linked (GlcNAc) threonine		UniProt GlyGen
313	O-linked (GlcNAc) threonine		UniProt GlyGen
		G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying entries **21 - 25** of 25 in total

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Pathway Name	Organism
Regulation of TP53 Activity through Association with Co-factors	Rattus norvegicus
Regulation of TP53 Degradation	Rattus norvegicus
Regulation of localization of FOXO transcription factors	Rattus norvegicus
TP53 Regulates Metabolic Genes	Rattus norvegicus
VEGFR2 mediated vascular permeability	Rattus norvegicus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

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Summary

External Links

Annotation

International Collaboration

Acknowledgements