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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Tumor necrosis factor ligand superfamily member 6
Summary
- UniProt ID
- P48023
- Gene Symbol
-
- FASLG
- APT1LG1
- CD95L
- FASL
- TNFSF6
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Apoptosis
- Cell membrane
- Cytokine
- Cytoplasmic vesicle
- Disulfide bond
- Glycoprotein
- Lysosome
- Nucleus
- Reference proteome
- Repressor
- Secreted
- Signal-anchor
- Transcription regulation
- Transmembrane helix
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| cytokine activity |
| death receptor binding |
| tumor necrosis factor receptor binding |
| signaling receptor binding |
Sequence
MQQPFNYPYPQIYWVDSSASSPWAPPGTVLPCPTSVPRRPGQRRPPPPPPPPPLPPPPPPPPLPPLPLPPLKKRGNHSTGLCLLVMFFMVLVALVGLGLGMFQLFHLQKELAELRESTSQMHTASSLEKQIGHPSPPPEKKELRKVAHLTGKSNSRSMPLEWEDTYGIVLLSGVKYKKGGLVINETGLYFVYSKVYFRGQSCNNLPLSHKVYMRNSKYPQDLVMMEGKMMSYCTTGQMWARSSYLGAVFNLTSADHLYVNVSELSLVNFEESQTFFGLYKL
Glycosylation Sites
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| CASP8 activity is inhibited | Homo sapiens |
| Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models | Homo sapiens |
| Dimerization of procaspase-8 | Homo sapiens |
| FOXO-mediated transcription of cell death genes | Homo sapiens |
| FasL/ CD95L signaling | Homo sapiens |
| Interleukin-4 and Interleukin-13 signaling | Homo sapiens |
| Ligand-dependent caspase activation | Homo sapiens |
| RIPK1-mediated regulated necrosis | Homo sapiens |
| Regulation by c-FLIP | Homo sapiens |
