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Extracellular calcium-sensing receptor
Summary
- UniProt ID
- P48442
- Gene Symbol
-
- Casr
- Gprc2a
- Pcar1
- Organism
- Rattus norvegicus (Norway rat)
External Links
- PubChem
- P48442
Annotation
- Keyword
-
- Calcium
- Cell membrane
- Disulfide bond
- G-protein coupled receptor
- Glycoprotein
- Metal-binding
- Phosphoprotein
- Reference proteome
- Signal
- Transmembrane helix
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| positive regulation of ERK1 and ERK2 cascade |
| positive regulation of calcium ion import |
| GO Term |
|---|
| plasma membrane |
| axon |
| neuronal cell body |
| axon terminus |
| basolateral plasma membrane |
| apical plasma membrane |
| cell surface |
Sequence
MASYSCCLALLALAWHSSAYGPDQRAQKKGDIILGGLFPIHFGVAAKDQDLKSRPESVECIRYNFRGFRWLQAMIFAIEEINSSPSLLPNMTLGYRIFDTCNTVSKALEATLSFVAQNKIDSLNLDEFCNCSEHIPSTIAVVGATGSGVSTAVANLLGLFYIPQVSYASSSRLLSNKNQYKSFLRTIPNDEHQATAMADIIEYFRWNWVGTIAADDDYGRPGIEKFREEAEERDICIDFSELISQYSDEEEIQQVVEVIQNSTAKVIVVFSSGPDLEPLIKEIVRRNITGRIWLASEAWASSSLIAMPEYFHVVGGTIGFGLKAGQIPGFREFLQKVHPRKSVHNGFAKEFWEETFNCHLQEGAKGPLPVDTFVRSHEEGGNRLLNSSTAFRPLCTGDENINSVETPYMDYEHLRISYNVYLAVYSIAHALQDIYTCLPGRGLFTNGSCADIKKVEAWQVLKHLRHLNFTNNMGEQVTFDECGDLVGNYSIINWHLSPEDGSIVFKEVGYYNVYAKKGERLFINEEKILWSGFSREVPFSNCSRDCQAGTRKGIIEGEPTCCFECVECPDGEYSGETDASACDKCPDDFWSNENHTSCIAKEIEFLAWTEPFGIALTLFAVLGIFLTAFVLGVFIKFRNTPIVKATNRELSYLLLFSLLCCFSSSLFFIGEPQDWTCRLRQPAFGISFVLCISCILVKTNRVLLVFEAKIPTSFHRKWWGLNLQFLLVFLCTFMQILICIIWLYTAPPSSYRNHELEDEIIFITCHEGSLMALGSLIGYTCLLAAICFFFAFKSRKLPENFNEAKFITFSMLIFFIVWISFIPAYASTYGKFVSAVEVIAILAASFGLLACIFFNKVYIILFKPSRNTIEEVRSSTAAHAFKVAARATLRRPNISRKRSSSLGGSTGSIPSSSISSKSNSEDRFPQPERQKQQQPLSLTQQEQQQQPLTLHPQQQQQPQQPRCKQKVIFGSGTVTFSLSFDEPQKNAMAHRNSMRQNSLEAQRSNDTLGRHQALLPLQCADADSEMTIQETGLQGPMVGDHQPEMESSDEMSPALVMSTSRSFVISGGGSSVTENVLHS
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 90 | N-linked (GlcNAc...) asparagine |
|
||
| 130 | N-linked (GlcNAc...) asparagine |
|
||
| 261 | N-linked (GlcNAc...) asparagine |
|
||
| 287 | N-linked (GlcNAc...) asparagine |
|
||
| 386 | N-linked (GlcNAc...) asparagine |
|
||
| 446 | N-linked (GlcNAc...) asparagine |
|
||
| 468 | N-linked (GlcNAc...) asparagine |
|
||
| 488 | N-linked (GlcNAc...) asparagine |
|
||
| 541 | N-linked (GlcNAc...) asparagine |
|
||
| 594 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Class C/3 (Metabotropic glutamate/pheromone receptors) | Rattus norvegicus |
| G alpha (i) signalling events | Rattus norvegicus |
| G alpha (q) signalling events | Rattus norvegicus |
