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Prelamin-A/C

Summary

UniProt ID

P48678

Gene Symbol

Lmna
Lmn1

Organism

Mus musculus (house mouse)

External Links

GlyGen: P48678
PubChem: P48678
The O-GlcNAc Database: P48678
RaftProt: P48678
O-GlcNAcAtlas: P48678

Annotation

Keyword

3D-structure
Acetylation
Alternative splicing
Coiled coil
Direct protein sequencing
Glycoprotein
Intermediate filament
Isopeptide bond
Methylation
Nucleus
Phosphoprotein
Prenylation
Reference proteome
Ubl conjugation

Gene Ontology (GO)

Displaying entries **1 - 10** of 25 in total

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GO Term
protein import into nucleus
heterochromatin formation
negative regulation of release of cytochrome c from mitochondria
cellular senescence
negative regulation of cardiac muscle hypertrophy in response to stress
negative regulation of extrinsic apoptotic signaling pathway
nucleus organization
nuclear envelope organization
nuclear migration
muscle organ development

Displaying **all 10** entries
GO Term
nucleus
nuclear envelope
nucleoplasm
site of double-strand break
perinuclear region of cytoplasm
nuclear membrane
nuclear matrix
nuclear speck
lamin filament
nuclear lamina

Displaying **all 3** entries
GO Term
structural constituent of cytoskeleton
protein phosphatase 1 binding
structural constituent of nuclear lamina

Annotation information from UniProt.

Sequence

METPSQRRATRSGAQASSTPLSPTRITRLQEKEDLQELNDRLAVYIDRVRSLETENAGLRLRITESEEVVSREVSGIKAAYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKARNTKKEGDLLAAQARLKDLEALLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAKKQLQDEMLRRVDAENRLQTLKEELDFQKNIYSEELRETKRRHETRLVEIDNGKQREFESRLADALQELRAQHEDQVEQYKKELEKTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQLAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEYQELLDIKLALDMEIHAYRKLLEGEEERLRLSPSPTSQRSRGRASSHSSQSQGGGSVTKKRKLESSESRSSFSQHARTSGRVAVEEVDEEGKFVRLRNKSNEDQSMGNWQIRRQNGDDPLMTYRFPPKFTLKAGQVVTIWASGAGATHSPPTDLVWKAQNTWGCGSSLRTALINSTGEEVAMRKLVRSLTMVEDNEDDDEDGEELLHHHRGSHCSGSGDPAEYNLRSRTVLCGTCGQPADKAAGGAGAQVGGSISSGSSASSVTVTRSFRSVGGSGGGSFGDNLVTRSYLLGNSSPRSQSSQNCSIM

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying entries **1 - 10** of 14 in total

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Position	GlyTouCan ID	Source
456	G47702MW	GlyGen
532	G53434XO	GlyGen
611	G49108TO	GlyGen The O-GlcNAc Database
613	G49108TO	GlyGen The O-GlcNAc Database
614	G49108TO	GlyGen The O-GlcNAc Database
616	G49108TO	GlyGen
617	G49108TO	GlyGen
619	G49108TO	GlyGen
620	G49108TO	GlyGen
622	G49108TO	GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 3** entries
Pathway Name	Organism
Breakdown of the nuclear lamina	Mus musculus
Depolymerization of the Nuclear Lamina	Mus musculus
Initiation of Nuclear Envelope (NE) Reformation	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

International Collaboration

Acknowledgements