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Prelamin-A/C
Summary
- UniProt ID
- P48679
- Gene Symbol
-
- Lmn1
- Lmna
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- Acetylation
- Alternative splicing
- Coiled coil
- Direct protein sequencing
- Glycoprotein
- Intermediate filament
- Isopeptide bond
- Methylation
- Nucleus
- Phosphoprotein
- Prenylation
- Reference proteome
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| lamin filament |
| nucleus |
| nuclear envelope |
| nuclear membrane |
| nucleoplasm |
| perinuclear region of cytoplasm |
| nuclear lamina |
| nuclear matrix |
| site of double-strand break |
| GO Term |
|---|
| structural constituent of cytoskeleton |
| protein phosphatase 1 binding |
| structural constituent of nuclear lamina |
Sequence
METPSQRRPTRSGAQASSTPLSPTRITRLQEKEDLQELNDRLAVYIDRVRSLETENAGLRLRITESEEVVSREVSGIKAAYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKARNTKKEGDLLAAQARLKDLEALLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAKKQLQDEMLRRVDAENRLQTLKEELDFQKNIYSEELRETKRRHETRLVEIDNGKQREFESRLADALQELRAQHEDQVEQYKKELEKTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQLAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEYQELLDIKLALDMEIHAYRKLLEGEEERLRLSPSPTSQRSRGRASSHSSQSQGGGSVTKKRKLESSESRSSFSQHARTSGRVAVEEVDEEGKFVRLRNKSNEDQSMGNWQIKRQNGDDPLMTYRFPPKFTLKAGQVVTIWASGAGATHSPPTDLVWKAQNTWGCGTSLRTALINATGEEVAMRKLVRSLTMVEDNDDEEEDGDELLHHHRGSHCSSSGDPAEYNLRSRTVLCGTCGQPADKAASGSGAQVGGSISSGSSASSVTVTRSFRSVGGSGGGSFGDNLVTRSYLLGNSSPRTQSSQNCSIM
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Breakdown of the nuclear lamina | Rattus norvegicus |
| Depolymerization of the Nuclear Lamina | Rattus norvegicus |
| Initiation of Nuclear Envelope (NE) Reformation | Rattus norvegicus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:224 | transient cerebral ischemia |
