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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
Summary
- UniProt ID
- P48736
- Gene Symbol
-
- PIK3CG
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- P48736
- PubChem
- P48736
- SwissLipids
- The Human Metabolome Database
- HMDBP01392
- The O-GlcNAc Database
- P48736
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Angiogenesis
- Cell membrane
- Chemotaxis
- Cytoplasm
- Disease variant
- Endocytosis
- Immunity
- Inflammatory response
- Lipid metabolism
- Phosphoprotein
- Reference proteome
- Serine/threonine-protein kinase
- Gene Ontology (GO)
| GO Term |
|---|
| cytosol |
| phosphatidylinositol 3-kinase complex, class IA |
| phosphatidylinositol 3-kinase complex, class IB |
| cytoplasm |
| plasma membrane |
| membrane |
Sequence
MELENYKQPVVLREDNCRRRRRMKPRSAAASLSSMELIPIEFVLPTSQRKCKSPETALLHVAGHGNVEQMKAQVWLRALETSVAADFYHRLGPHHFLLLYQKKGQWYEIYDKYQVVQTLDCLRYWKATHRSPGQIHLVQRHPPSEESQAFQRQLTALIGYDVTDVSNVHDDELEFTRRGLVTPRMAEVASRDPKLYAMHPWVTSKPLPEYLWKKIANNCIFIVIHRSTTSQTIKVSPDDTPGAILQSFFTKMAKKKSLMDIPESQSEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNGEEIHVVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRKFRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKIKDLPKGALLNLQIYCGKAPALSSKASAESPSSESKGKVQLLYYVNLLLIDHRFLLRRGEYVLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEGDRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQQEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAYLRGCGTAMLHDFTQQVQVIEMLQKVTLDIKSLSAEKYDVSSQVISQLKQKLENLQNSQLPESFRVPYDPGLKAGALAIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQDMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTGAFKDEVLNHWLKEKSPTEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSPHFQKFQDICVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGWTVQFNWFLHLVLGIKQGEKHSA
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 240 |
|
|||
| 250 |
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Erythropoietin activates Phosphoinositide-3-kinase (PI3K) | Homo sapiens |
| G beta:gamma signalling through PI3Kgamma | Homo sapiens |
| GPVI-mediated activation cascade | Homo sapiens |
| Synthesis of PIPs at the plasma membrane | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:2986 | IgA glomerulonephritis | |
| DOID:2987 | familial mediterranean fever | |
| DOID:299 | adenocarcinoma | |
| DOID:2994 | germ cell cancer | |
| DOID:2998 | testicular cancer | |
| DOID:3007 | breast ductal carcinoma | |
| DOID:3008 | invasive ductal carcinoma | |
| DOID:3016 | breast malignant phyllodes tumor | |
| DOID:302 | substance abuse | |
| DOID:303 | substance-related disorder |
