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Integrin beta-1

Summary

UniProt ID

P49134

Gene Symbol

Itgb1

Organism

Rattus norvegicus (Norway rat)

External Links

PubChem: P49134

Annotation

Keyword

Acetylation
Calcium
Cell adhesion
Cell junction
Cell membrane
Cell projection
Disulfide bond
EGF-like domain
Endosome
Glycoprotein
Integrin
Isopeptide bond
Magnesium
Metal-binding
Myogenesis
Phosphoprotein
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix
Ubl conjugation

Gene Ontology (GO)

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GO Term
phagocytosis
cell adhesion
leukocyte cell-cell adhesion
neuroblast proliferation
muscle organ development
regulation of G protein-coupled receptor signaling pathway
cell population proliferation
negative regulation of cell population proliferation
germ cell migration
neuron differentiation

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GO Term
ruffle membrane
integrin alpha1-beta1 complex
integrin alpha2-beta1 complex
integrin alpha3-beta1 complex
integrin alpha5-beta1 complex
integrin alpha7-beta1 complex
integrin alpha9-beta1 complex
integrin alpha10-beta1 complex
integrin alpha11-beta1 complex
integrin alphav-beta1 complex

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GO Term
protein-containing complex binding
kinase binding
protein kinase binding
cell adhesion molecule binding
alpha-actinin binding
protein domain specific binding
C-X3-C chemokine binding
protein tyrosine kinase binding
protein heterodimerization activity
magnesium ion binding

Annotation information from UniProt.

Sequence

MNLQLVFWIGLISLICSVFGQTDKNRCLKANAKSCGECIQAGPNCGWCTNTTFLQEGMPTSARCDDLEALKKKGCHPSDIENPRGSQTIKKNKNVTNRSKGMAEKLRPEDITQIQPQQLLLKLRSGEPQKFTLKFKRAEDYPIDLYYLMDLSYSMKDDLENVKSLGTDLMNEMRRITSDFRIGFGSFVEKTVMPYISTTPAKLRNPCTSEQNCTSPFSYKNVLSLTDRGEFFNELVGQQRISGNLDSPEGGFDAIMQVAVCGSLIGWRNVTRLLVFSTDAGFHFAGDGKLGGIVLPNDGQCHLENNVYTMSHYYDYPSIAHLVQKLSENNIQTIFAVTEEFQPVYKELKNLIPKSAVGTLSGNSSNVIQLIIDAYNSLSSEVILENSKLPDGVTINYKSYCKNGVNGTGENGRKCSNISIGDEVQFEISITANKCPNKESENQLKLNPLGFTEEVEVVLQFICKCNCQSHGIPASPKCHEGNGTFECGACRCNEGRVGRHCECSTDEVNSEDMDAYCRKENSSEICSNNGECVCGQCVCRKRENTNEIYSGKFCECDNFNCDRSNGLICGGNGVCRCRVCECYPNYTGSACDCSLDTVPCVATNGQICNGRGICECGACKCTDPKFQGPTCETCQTCLGVCAEHKECVQCRAFNKGEKKDTCAQECSHFNLTKVESREKLPQPVQVDPVTHCKEKDIDDCWFYFTYSVNSKGEAHVHVVETPDCPTGPDIIPIVAGVVAGIVLIGLALLLIWKLLMIIHDRREFAKFEKEKMNAKWDTGENPIYKSAVTTVVNPKYEGK

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

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Position	Description	PubMed ID	GlyTouCan ID	Source
585	N-linked (GlcNAc...) asparagine			UniProt
670	N-linked (GlcNAc...) asparagine			UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

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Pathway Name	Organism
MET activates PTK2 signaling	Rattus norvegicus
MET interacts with TNS proteins	Rattus norvegicus
Molecules associated with elastic fibres	Rattus norvegicus
RAC1 GTPase cycle	Rattus norvegicus
RAC2 GTPase cycle	Rattus norvegicus
RHOG GTPase cycle	Rattus norvegicus
Signal transduction by L1	Rattus norvegicus
Syndecan interactions	Rattus norvegicus
TGF-beta receptor signaling activates SMADs	Rattus norvegicus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

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Other Information

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Summary

External Links

Annotation

International Collaboration

Acknowledgements