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Neuronal acetylcholine receptor subunit alpha-7

Summary

UniProt ID

P49582

Gene Symbol

Chrna7
Acra7

Organism

Mus musculus (house mouse)

External Links

GlyGen: P49582
PubChem: P49582

Annotation

Keyword

Cell membrane
Disulfide bond
Glycoprotein
Ligand-gated ion channel
Postsynaptic cell membrane
Receptor
Reference proteome
Signal
Transmembrane helix

Gene Ontology (GO)

Displaying entries **51 - 54** of 54 in total

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GO Term
positive regulation of amyloid-beta formation
response to amyloid-beta
regulation of amyloid fibril formation
positive regulation of CoA-transferase activity

Displaying entries **21 - 23** of 23 in total

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GO Term
dendritic spine
spine apparatus membrane
postsynaptic specialization membrane

Displaying **all 8** entries
GO Term
acetylcholine receptor activity
protein kinase binding
acetylcholine-gated monoatomic cation-selective channel activity
acetylcholine binding
transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
ATPase binding
adenylate cyclase binding
scaffold protein binding

Annotation information from UniProt.

Sequence

MCGRRGGIWLALAAALLHVSLQGEFQRRLYKELVKNYNPLERPVANDSQPLTVYFSLSLLQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNMSEYPGVKNVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNASGHCQYLPPGIFKSSCYIDVRWFPFDVQQCKLKFGSWSYGGWSLDLQMQEADISSYIPNGEWDLMGIPGKRNEKFYECCKEPYPDVTYTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSGEKISLGITVLLSLTVFMLLVAEIMPATSDSVPLIAQYFASTMIIVGLSVVVTVIVLRYHHHDPDGGKMPKWTRIILLNWCAWFLRMKRPGEDKVRPACQHKPRRCSLASVELSAGAGPPTSNGNLLYIGFRGLEGMHCAPTPDSGVVCGRLACSPTHDEHLMHGTHPSDGDPDLAKILEEVRYIANRFRCQDESEVICSEWKFAACVVDRLCLMAFSVFTIICTIGILMSAPNFVEAVSKDFA

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 3** entries
Position	Description	PubMed ID	Source
46	N-linked (GlcNAc...) asparagine	32783947	UniProt GlyGen
90	N-linked (GlcNAc...) asparagine	32783947	UniProt GlyGen
133	N-linked (GlcNAc...) asparagine	32783947	UniProt GlyGen