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Thrombopoietin

Summary

UniProt ID

P49745

Gene Symbol

Thpo

Organism

Rattus norvegicus (Norway rat)

External Links

PubChem: P49745

Annotation

Keyword

Cytokine
Disulfide bond
Glycoprotein
Hormone
Reference proteome
Secreted
Signal

Gene Ontology (GO)

Displaying entries **1 - 10** of 15 in total

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GO Term
positive regulation of protein phosphorylation
positive regulation of MAPK cascade
receptor signaling pathway via STAT
response to lipopolysaccharide
thrombopoietin-mediated signaling pathway
positive regulation of ERK1 and ERK2 cascade
cell population proliferation
positive regulation of cell population proliferation
myeloid cell differentiation
megakaryocyte differentiation

Displaying **all 2** entries
GO Term
extracellular region
extracellular space

Displaying **all 3** entries
GO Term
cytokine activity
hormone activity
signaling receptor binding

Annotation information from UniProt.

Sequence

MELTDLLLVAILLLTARLTLSSPVPPACDPRLLNKLLRDSYLLHSRLSQCPDVNPLSIPVLLPAVDFSLGEWKTQTEQSKAQDILGAVSLLLEGVMAARGQLEPSCLSSLLGQLSGQVRLLLGALQGLLGTQLPPQGRTTAHKDPSALFLSLQQLLRGKVRFLLLVEGPALCVRRTLPTTAVPSRTSQLLTLNKFPNRTSGLLETNFSVVARTAGPGLLNRLQGFRAKIIPGQLNQTSGSLDQIPGYLNGTHEPVNGTHGLFAGTSLQTLEAPDVVPGAFNKGSLPLNLQSGLPPIPSLAADGYTLFPPSPTFPTPGSPPQLPPVS

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 5** entries
Position	Description	Source
197	N-linked (GlcNAc...) asparagine	UniProt
206	N-linked (GlcNAc...) asparagine	UniProt
235	N-linked (GlcNAc...) asparagine	UniProt
249	N-linked (GlcNAc...) asparagine	UniProt
256	N-linked (GlcNAc...) asparagine	UniProt